2-(5-Benzo[1,3]dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrate hydrochloride
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- ₹3300 - ₹85376.78
- Product name: 2-(5-Benzo[1,3]dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrate hydrochloride
- CAS: 694433-59-5
- MF: C20H21N3O2
- MW: 335.4
- EINECS:
- MDL Number:MFCD20926329
- Synonyms:2-(5-Benzo[1,3]dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrate hydrochloride;SB-505124 hydrate hydrochloride;2-(5-Benzo[1,3]dioxol-5-yl-2-tert-butyl-3H-iMidazol-4-yl)-6-Methylpyridine;2-[4-(1,3-Benzodioxol-5-yl)-2-(1,1- diMethylethyl)-1H-iMidazol-5-yl]-6-Methyl-pyridine;2-[4-(1,3-Benzodioxol-5-yl)-2-(tert-butyl)-1H-imidazol-5-yl]-6-methylpyridine;SB-505124 hydrochloride hydrate;2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-imidazol-5-yl)-6-methylpyridine;2-[4-(1,3-Benzodioxol-5-yl)-2-(tert-butyl)-1H-imidazol-5-yl]-6-methylpyridine SB505124
4 prices
Selected condition:
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerTCI Chemicals (India)
- Product numberB6056
- Product descriptionSB-505124
- Packaging5MG
- Price₹3300
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberB6056
- Product descriptionSB-505124
- Packaging25MG
- Price₹9900
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberS4696
- Product descriptionSB-505124 hydrochloride hydrate ≥98% (HPLC)
- Packaging5MG
- Price₹21898.98
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberS4696
- Product descriptionSB-505124 hydrochloride hydrate ≥98% (HPLC)
- Packaging25MG
- Price₹85376.78
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | B6056 | SB-505124 | 5MG | ₹3300 | 2022-05-26 | Buy |
TCI Chemicals (India) | B6056 | SB-505124 | 25MG | ₹9900 | 2022-05-26 | Buy |
Sigma-Aldrich(India) | S4696 | SB-505124 hydrochloride hydrate ≥98% (HPLC) | 5MG | ₹21898.98 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | S4696 | SB-505124 hydrochloride hydrate ≥98% (HPLC) | 25MG | ₹85376.78 | 2022-06-14 | Buy |
Properties
Melting point :168 °C
Boiling point :509.7±50.0 °C(Predicted)
Density :1.202
storage temp. :Sealed in dry,2-8°C
solubility :DMSO: >10mg/mL
pka :11.26±0.10(Predicted)
form :powder
color :yellow
Boiling point :509.7±50.0 °C(Predicted)
Density :1.202
storage temp. :Sealed in dry,2-8°C
solubility :DMSO: >10mg/mL
pka :11.26±0.10(Predicted)
form :powder
color :yellow
Safety Information
Symbol(GHS): |
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Description
SB-505124 inhibits the TGF-β1 receptor serine/threonine kinase ALK5 with an IC50 value of 47 nM. Though it is a less potent antagonist of ALK4 (IC50 = 129 nM) and ALK7, SB-505124 selectively and concentration-dependently inhibits ALK4-, ALK5-, and ALK7-dependent activation of downstream SMAD2 and SMAD3 and TGF-β–induced MAP kinase pathway components without altering ALK1-3 or ALK6-induced SMAD signaling. In an assay determining in vitro phosphorylation of SMAD3, SB-505124 is more potent than SB-431452 with IC50 values of 47 versus 94 nM, respectively.More related product prices
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Suppliers and manufacturers
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CLEARSYNTH LABS LTD.
A.J Chemicals
TCI Chemicals (India) Pvt. Ltd.
ATK CHEMICAL COMPANY LIMITED
TargetMol Chemicals Inc.
Zhejiang J&C Biological Technology Co.,Limited
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₹1.00 /1KG
2-(5-Benzo[1,3]dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrate hydrochloride CAS:694433-59-5
2-(5-Benzo[1,3]dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrate hydrochloride CAS:694433-59-5