LY2109761
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- ₹0
- Product name: LY2109761
- CAS: 700874-71-1
- MF: C26H27N5O2
- MW: 441.52
- EINECS:
- MDL Number:MFCD12923354
- Synonyms:LY2109761/LY-2109761;LY2109761;Quinoline, 4-[5,6-dihydro-2-(2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]-7-[2-(4-Morpholinyl)ethoxy]-;4-[5,6-Dihydro-2-(2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]-7-[2-(4-morpholinyl)ethoxy]quinoline;LY210976;4-[2-[4-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinolin-7-yl]oxyethyl]Morpholine;N-CYCLOPENTYL-WEI -ALANINE;N-CYCLOPENTYL-Β-ALANINE
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Properties
Boiling point :640.9±55.0 °C(Predicted)
Density :1.34
storage temp. :Store at -20°C
solubility :≥22.1 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form :solid
pka :6.27±0.10(Predicted)
color :White to yellow
Density :1.34
storage temp. :Store at -20°C
solubility :≥22.1 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form :solid
pka :6.27±0.10(Predicted)
color :White to yellow
Safety Information
Symbol(GHS): |
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Description
LY2109761 is a novel selective TGF-β receptor type I/II (TβRI/II) dual inhibitor with Ki of 38 nM and 300 nM in a cell-free assay, respectively; shown to negatively affect the phosphorylation of Smad2.More related product prices
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