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(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one

(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one Structure
  • ₹0
  • Product name: (S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
  • CAS: 870281-86-0
  • MF: C17H16FN3O
  • MW: 297.33
  • EINECS:
  • MDL Number:MFCD22124614
  • Synonyms:(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one;2-[(1S)-1-Aminopropyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone;Idelalisib INT;CAL-101 (N-1) Intermediate;(S)-2-(1-((9H-purin-6-yl-2,8-d2)amino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one;CAL10;IdelalisibIntermediates 1;2-[(1S)-1-aminopropyl]-5-fluoro-3-phenyl-3,4-dihydroquinazolin-4-one
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Boiling point :455.3±55.0 °C(Predicted)
Density :1.27±0.1 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :Chloroform (Slightly), DMSO (Slightly), Ethanol (Sparingly)
form :Solid
pka :8.23±0.29(Predicted)
color :Off-White

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

2-[(1S)-1-Aminoprpyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone is used as reagent/reactant in synthetic preparation of idelalisib using the HMDS/I2-catalyzed cyclocondensation and Boc deprotection of an (aminobutyrylamino)benzamide to a nonracemic quinazoline as the key step.

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2-Fluoro-6-nitro-N-phenylbenzamide CAL-101 (S)-tert-butyl (1-(5-fluoro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)propyl)carbaMate BOC-ABU-OH 2-Amino-6-fluorobenzoic acid

Related product price

Suppliers and manufacturers

Changzhou Rokechem Technology Co., Ltd.
(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
₹0.00 /1kg
(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one CAS:870281-86-0
career henan chemical co
(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
₹1.00 /1KG
(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one CAS:870281-86-0
A.J Chemicals Pharmaffiliates Analytics and Synthetics P. Ltd Pharma Affiliates SynZeal Research Pvt Ltd
Capot Chemical Co.,Ltd.
Shanghai Daken Advanced Materials Co.,Ltd
Fluoropharm Co., Ltd.
ATK CHEMICAL COMPANY LIMITED