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2-N-HEXYL-4-PENTYNOIC ACID

2-N-HEXYL-4-PENTYNOIC ACID Structure
  • ₹9200 - ₹41100
  • Product name: 2-N-HEXYL-4-PENTYNOIC ACID
  • CAS: 96017-59-3
  • MF: C11H18O2
  • MW: 182.26
  • EINECS:
  • MDL Number:MFCD00946863
  • Synonyms:2-(2-PROPYNYL)OCTANOIC ACID;2-N-HEXYL-4-PENTYNOIC ACID;2-PROPARGYLOCTANOIC ACID;2-Hexyl-4-pentynoic Acid;2-Propargyloctanoic Acid 2-(2-Propynyl)octanoic Acid;2-Hexyl-4-pentynoicAcid>2-(Prop-2-yn-1-yl)octanoic acid;Hexyl-4-pentynoic acid (HPA)
2 prices
Selected condition:

Brand

  • TCI Chemicals (India)

Package

  • 5G
  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberH0964
  • Product description2-Hexyl-4-pentynoic Acid
  • Packaging5G
  • Price₹9200
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberH0964
  • Product description2-Hexyl-4-pentynoic Acid
  • Packaging25G
  • Price₹41100
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) H0964 2-Hexyl-4-pentynoic Acid 5G ₹9200 2022-05-26 Buy
TCI Chemicals (India) H0964 2-Hexyl-4-pentynoic Acid 25G ₹41100 2022-05-26 Buy

Properties

Boiling point :287.1±23.0 °C(Predicted)
Density :0.94
refractive index :1.4450-1.4510
storage temp. :Inert atmosphere,Room Temperature
solubility :Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
form :oil
pka :4.24±0.21(Predicted)
color :Colorless
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

2-hexyl-4-Pentynoic acid is a derivative of valproic acid , an inhibitor of histone deacetylases (HDACs). It inhibits HDAC activity more potently (IC50 = 13 μM) than valproic acid (IC50 = 398 μM). 2-hexyl-4-Pentynoic acid induces histone hyperacetylation in cerebellar granule cells significantly at 5 μM. It also induces the expression of heat shock proteins Hsp70-1a and Hsp70-1b and protects cerebellar granule cells from glutamate-induced excitotoxicity when used at a concentration of 50 μM.

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