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Eflornithine hydrochloride hydrate

Eflornithine hydrochloride hydrate Structure
  • ₹10700
  • Product name: Eflornithine hydrochloride hydrate
  • CAS: 96020-91-6
  • MF: C6H15ClF2N2O3
  • MW: 236.64
  • EINECS:
  • MDL Number:MFCD00242734
  • Synonyms:2,5-diamino-2-(difluoromethyl)pentanoic acid;DMFO HCl/Eflornithine HCl;DFMO EFLORNITHINE;H-alpha-Difluoro-Me-DL-Orn-OH . HCl . H2O;2-(Difluoromethyl)ornithine hydrochloride hydrate;eflornithine,Eflornithinehydrochloridehydrate;Eflornithine hydrochloride hydrate;Eflornithine hydrochloride monohydrate
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Brand

  • TCI Chemicals (India)

Package

  • 200MG
  • ManufacturerTCI Chemicals (India)
  • Product numberE0947
  • Product descriptionEflornithine Hydrochloride Monohydrate
  • Packaging200MG
  • Price₹10700
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) E0947 Eflornithine Hydrochloride Monohydrate 200MG ₹10700 2022-05-26 Buy

Properties

Melting point :>210°C (dec.)
storage temp. :Inert atmosphere,2-8°C
solubility :Soluble in Water (up to 25 mg/ml).
form :White powder
color :White
Merck :14,3522
Stability :Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.
CAS DataBase Reference :96020-91-6

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

DL-α-Difluoromethylornithine (DFMO) is an irreversible inhibitor of ornithine decarboxylase that suppresses polyamine biosynthesis. DFMO displays antiangiogenic and cytostatic effects in tumor cells but must be used in combination with other chemotherapeutic agents to negate compensatory increases in polyamine content through alternate synthesis pathways. Through inhibition of polyamine synthesis, DFMO also demonstrates antiparasitic activity in a model of C. parvum infection.

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