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ChemicalBook > Product Catalogue >API >Synthetic Anti-infective Drugs >Quinolones >Lomefloxacin hydrochloride

Lomefloxacin hydrochloride

Lomefloxacin hydrochloride Structure
  • ₹1260 - ₹32583.25
  • Product name: Lomefloxacin hydrochloride
  • CAS: 98079-52-8
  • MF: C17H20ClF2N3O3
  • MW: 387.81
  • EINECS:627-337-1
  • MDL Number:MFCD00214312
  • Synonyms:1,4-dihydro-6,8-difluoro-1-ethyl-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylicacimonohydrochloride ;bareon ;ny198 ;sc-47111 ;1-ETHYL-6,8-DIFLUORO-1,4-DIHYDRO-7-[3-METHYL-1-PIPERAZINYL]-4-OXO-3-QUINOLINECARBOXYLIC ACID HYDROCHLORIDE;LOMEFLOXACIN HYDROCHLORIDE;Chimono;Lomebact
5 prices
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • SRL

Package

  • 1G
  • 5G
  • 10G
  • 1Gms
  • 5Gms
  • ManufacturerTCI Chemicals (India)
  • Product numberL0216
  • Product descriptionLomefloxacin Hydrochloride
  • Packaging5G
  • Price₹6500
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberL2906
  • Product descriptionLomefloxacin hydrochloride
  • Packaging1G
  • Price₹5748.08
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberL2906
  • Product descriptionLomefloxacin hydrochloride
  • Packaging10G
  • Price₹32583.25
  • Updated2022-06-14
  • Buy
  • ManufacturerSRL
  • Product number52737
  • Product descriptionLomefloxacin Hydrochloride (LMF), 98.5%
  • Packaging5Gms
  • Price₹3260
  • Updated2022-05-26
  • Buy
  • ManufacturerSRL
  • Product number52737
  • Product descriptionLomefloxacin Hydrochloride (LMF), 98.5%
  • Packaging1Gms
  • Price₹1260
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) L0216 Lomefloxacin Hydrochloride 5G ₹6500 2022-05-26 Buy
Sigma-Aldrich(India) L2906 Lomefloxacin hydrochloride 1G ₹5748.08 2022-06-14 Buy
Sigma-Aldrich(India) L2906 Lomefloxacin hydrochloride 10G ₹32583.25 2022-06-14 Buy
SRL 52737 Lomefloxacin Hydrochloride (LMF), 98.5% 5Gms ₹3260 2022-05-26 Buy
SRL 52737 Lomefloxacin Hydrochloride (LMF), 98.5% 1Gms ₹1260 2022-05-26 Buy

Properties

Melting point :290-3000C
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :1 M NaOH: soluble50mg/mL
form :powder to crystal
color :white to off-white
Merck :14,5562
CAS DataBase Reference :98079-52-8(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P501 Dispose of contents/container to..…

Description

Lomefloxacin hydrochloride is the hydrochloride form of Lomefloxacin. Lomefloxacin is a bactericidal fluoroquinolone agent that is active against gram-negative and gram-positive organisms. Lomefloxacin inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, which are needed for the transcription and replication of bacterial DNA. DNA gyrase is thought to be the primary quinolone target for gram-negative bacteria. Topoisomerase IV is thought to be the primary target in gram-positive organisms. The inhibition of the topoisomerases results in strand breakage of the bacterial chromosome, supercoiling, and resealing. Therefore, DNA replication and transcription is inhibited. Lomefloxacin can be used to treat many kinds of infections such as respiratory, urinary tract, obstetric, gynaecological, joint, skin, oral, ear, nose, throat and eye infections. Compared with other quinolone antibacterial drugs, lomefloxacin has certain advantages such as convenient administration and no necessity of theophylline dosage adjustment.

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