ABX-1431
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- Product name: ABX-1431
- CAS: 1446817-84-0
- MF: C20H22F9N3O2
- MW: 507.39
- EINECS:
- MDL Number:MFCD31735112
- Synonyms:CS-2856;ABX1431;ABX 1431;ABX-1431;1-Piperazinecarboxylic acid, 4-[[2-(1-pyrrolidinyl)-4-(trifluoromethyl)phenyl]methyl]-, 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ester;1,1,1,3,3,3-hexafluoropropan-2-yl 4-{[2-(pyrrolidin-1-yl)-4-(trifluoromethyl)phenyl]me thyl}piperazine-1-carboxylate;1,1,1,3,3,3-Hexafluoropropan-2-yl 4-(2-(pyrrolidin-1-yl)-4-(trifluoromethyl)benzyl)piperazine-1-carboxylate;ABX-1431,inhibit,ABX 1431,Monoacylglycerol lipase,ABX1431,MAGL,Inhibitor;Elcubragistat
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Properties
storage temp. :-20°C
solubility :Soluble in DMSO (>25 mg/ml)
form :solid
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
solubility :Soluble in DMSO (>25 mg/ml)
form :solid
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Safety Information
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Description
ABX-1431 (1446817-84-0) is a potent (IC50 = 14 nM in vitro, 2.2 nM in human PC3 cells) and very selective (>100-fold over hABHD6, >200-fold over hPLA2G7) inhibitor of monoacylglycerol lipase (MAGL).1 Active in a rat formalin pain test at 3mg/kg. Orally bioavailable and CNS penetrant.More related product prices
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Suppliers and manufacturers
A.J Chemicals
ATK CHEMICAL COMPANY LIMITED
Career Henan Chemica Co
InvivoChem
Hangzhou MolCore BioPharmatech Co.,Ltd.
TargetMol Chemicals Inc.
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd
Aladdin Scientific
Wuhan Jingkang en Biomedical Technology Co., Ltd
Olix (Shanghai) Pharmaceutical Technology Co., Ltd