N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine
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- ₹0
- Product name: N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine
- CAS: 1097917-15-1
- MF: C29H40N8O3S
- MW: 580.74
- EINECS:200-258-5
- MDL Number:MFCD21609265
- Synonyms:ASP3026;ASP 3026;ASP-3026;N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfon;ASP 3026;N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine;1,3,5-Triazine-2,4-diamine, N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-;N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine ASP 3026;ASP 3026; ASP-3026;CS-286
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
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Properties
Boiling point :794.3±70.0 °C(Predicted)
Density :1.276
storage temp. :Store at -20°C
solubility :insoluble in H2O; ≥14.53 mg/mL in DMSO; ≥4.9 mg/mL in EtOH with gentle warming and ultrasonic
form :solid
pka :8.14±0.42(Predicted)
color :White to off-white
Density :1.276
storage temp. :Store at -20°C
solubility :insoluble in H2O; ≥14.53 mg/mL in DMSO; ≥4.9 mg/mL in EtOH with gentle warming and ultrasonic
form :solid
pka :8.14±0.42(Predicted)
color :White to off-white
Safety Information
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Signal word: | Warning | |||||||
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Description
ASP3026 is an ATP-competitive, second-generation ALK inhibitor (IC50 = 3.5 nM) that also inhibits ROS (IC50 = 8.9 nM) and ACK (IC50 = 5.8 nM). It inhibits neuroblastoma-activating ALK mutants F1174L (IC50 = 10 nM) and R1275Q (IC50 = 5.4 nM) and demonstrates antitumor activity in xenograft mouse models. ASP3026 has been shown to overcome crizotinib resistance in non-small cell lung cancer, and is currently being evaluated in clinical trials of patients with ALK-positive solid tumors.More related product prices
PF-06463922 Crizotinib AP26113 ALK/IGF1R inhibitor 1256580-46-7 Ceritinib (LDK378) ABX-1431 936091-14-4 ASP-2215 SGI 7079 XL 228 UNC 0631 AGI6780Related product price
- Crizotinib
₹13174.03 - AGI6780
₹14440.55-58151.9
Suppliers and manufacturers
CLEARSYNTH LABS LTD.
ATK CHEMICAL COMPANY LIMITED
CONIER CHEM AND PHARMA LIMITED
TargetMol Chemicals Inc.
Dideu Industries Group Limited
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
ShenZhen Trendseen Biological Technology Co.,Ltd.
Henan Fengda Chemical Co., Ltd