ANP 1-28, HUMAN
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- Product name: ANP 1-28, HUMAN
- CAS: 89213-87-6
- MF: C127H203N45O39S3
- MW: 3080.44
- EINECS:686-482-9
- MDL Number:MFCD00076226
- Synonyms:Atrial natriureticpeptide-28 (huMan) (9CI);Atrial Natriuretic Factor (1-28) (huMan) αhANF, Carperitide;Carperitide Acetate;ATRIAL NATRIURETIC PEPTIDE HUMAN, 1-28;ATRIAL NATRIURETIC PEPTIDE 1-28, HUMAN;ATRIAL NATRIURETIC PEPTIDE (1-28), HUMAN, PORCINE;ATRIAL NATRIURETIC FACTOR 1-28, HUMAN;ATRIAL NATRIURETIC FACTOR (1-28) (HUMAN, CANINE)
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Properties
Density :1.55±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Water: 1 mg/ml
form :A lyophilized powder
Sequence :H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH，(Disulfide bridge: Cys-Cys)
storage temp. :Store at -20°C
solubility :Water: 1 mg/ml
form :A lyophilized powder
Sequence :H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH，(Disulfide bridge: Cys-Cys)
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Carperitide is the α-human atrial natriuretic peptide (α-hANP) produced by recombinant technology. It was introduced in Japan as a treatment for acute congestive heart failure (CHF). In dogs with CHF, carperitide significantly reduced the elevated left ventricular end-diastolic pressure and the index of myocardial oxygen consumption (systolic blood pressure x heart rate). In a clinical trial, carperitide was effective in improving hemodynamics and symptoms in 60% of patients with acute CHF. Carperitide was reported to be well tolerated with no significant adverse effects clinically. A beneficial effect on hemodynamics has been reported in chronic heart failure patients. Carperitide is also in clinical trials for maintenance of blood pressure during surgical operations.More related product prices
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Suppliers and manufacturers
Shenzhen Nexconn Pharmatechs Ltd
Xi'an Kono chem co., Ltd.,
Chongqing Chemdad Co., Ltd
Cellmano Biotech Limited
Hebei Bonster Technology Co.,Limited
