API-2
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- ₹27679.53 - ₹112699.08
- Product name: API-2
- CAS: 35943-35-2
- MF: C13H16N6O4
- MW: 320.3
- EINECS:
- MDL Number:MFCD00932413
- Synonyms:API-2;6-AMINO-4-METHYL-8-(BETA-D-RIBOFURANOSYL)-4H,8H-PYRROLO[4,3,2-DE]PYRIMIDO[4,5-C]PYRIDAZINE;AKT/PKB SIGNALING INHIBITOR-2;AKT INHIBITOR V;1,5-DIHYDRO-5-METHYL-1-BETA-D-RIBOFURANOSYL-1,4,5,6,8-PENTAAZAACENAPHTHYLEN-3-AMINE;1,4,5,6,8-pentaazaacenaphthylen-3-amine,1,5-dihydro-5-methyl-1-beta-d-ribofura ;API-2 (Tricirbine);TRICIRIBINE
4 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 400μL
- 2MG
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberT3830
- Product descriptionTriciribine hydrate ≥97% (HPLC)
- Packaging5MG
- Price₹27679.53
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number124038
- Product descriptionInSolution Akt Inhibitor V, Triciribine - CAS 35943-35-2 - Calbiochem The InSolution Akt Inhibitor V, Triciribine, also referenced under CAS 35943-35-2, controls the biological activity of Akt. This small molecule/inhibi
- Packaging2MG
- Price₹28660
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSAB1303874
- Product descriptionANTI-MYO1A (CENTER S291) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution
- Packaging400μL
- Price₹47796.6
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberT3830
- Product descriptionTriciribine hydrate ≥97% (HPLC)
- Packaging25MG
- Price₹112699.08
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | T3830 | Triciribine hydrate ≥97% (HPLC) | 5MG | ₹27679.53 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 124038 | InSolution Akt Inhibitor V, Triciribine - CAS 35943-35-2 - Calbiochem The InSolution Akt Inhibitor V, Triciribine, also referenced under CAS 35943-35-2, controls the biological activity of Akt. This small molecule/inhibi | 2MG | ₹28660 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SAB1303874 | ANTI-MYO1A (CENTER S291) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution | 400μL | ₹47796.6 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T3830 | Triciribine hydrate ≥97% (HPLC) | 25MG | ₹112699.08 | 2022-06-14 | Buy |
Properties
Melting point :207 °C (decomp)
Boiling point :459.21°C (rough estimate)
Density :1.2633 (rough estimate)
refractive index :1.7000 (estimate)
storage temp. :Store at RT
solubility :DMSO: >10mg/mL
form :powder
pka :12.35±0.70(Predicted)
color :tan
InChIKey :HOGVTUZUJGHKPL-HTVVRFAVSA-N
Boiling point :459.21°C (rough estimate)
Density :1.2633 (rough estimate)
refractive index :1.7000 (estimate)
storage temp. :Store at RT
solubility :DMSO: >10mg/mL
form :powder
pka :12.35±0.70(Predicted)
color :tan
InChIKey :HOGVTUZUJGHKPL-HTVVRFAVSA-N
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
Triciribine, also known as API-2, suppresses the phosphorylation level and kinase activity of Akt. Akt kinase inhibition has been shown to induce apoptosis and cell growth in cancer cell research. Triciribine can selectively inhibit Akt1, Akt2, and Akt3 without inhibiting known upstream activators,PDK1 and PI 3-Kinase, of Akt. Studies show that Triciribine in duces apoptosis and inhibits cell growth in cells that express atypical Akt1. Additionally, Triciribine has antineoplastic and antiviral activity at low micromolar and submicromolar concentrations, and has been demonstrated to inhibit incorporation of amino acids into proteins and purine nucleotide synthesis.Related product price
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₹27679.53-112699.08 - 189028-93-1
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