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ARG-GLY-ASP-SER

ARG-GLY-ASP-SER Structure
  • ₹8151.23 - ₹27019.2
  • Product name: ARG-GLY-ASP-SER
  • CAS: 91037-65-9
  • MF: C15H27N7O8
  • MW: 433.42
  • EINECS:1592732-453-0
  • MDL Number:MFCD00076452
  • Synonyms:Fibronectin tetrapeptide;L-Arginylglycyl-L-alpha-aspartyl-L-serine;L-Serine, L-arginylglycyl-L-alpha-aspartyl-;L-Serine, N-(N-(N-L-arginylglycyl)-L-alpha-aspartyl)-;arginyl-glycyl-aspartyl-serine ;RGDS;RGDS 1/2ACOH 2H2O;L-Serine,N-[N-(N-L-arginylglycyl)-L-a-aspartyl]-
4 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 2MG
  • 5MG
  • 10MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberA9041
  • Product descriptionArg-Gly-Asp-Ser ≥95% (HPLC)
  • Packaging10MG
  • Price₹27019.2
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number03-34-0002
  • Product descriptionH-Arg-Gly-Asp-Ser-OH - CAS 91037-65-9 - Calbiochem
  • Packaging25MG
  • Price₹18980
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA9041
  • Product descriptionArg-Gly-Asp-Ser ≥95% (HPLC)
  • Packaging5MG
  • Price₹14743.65
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA9041
  • Product descriptionArg-Gly-Asp-Ser ≥95% (HPLC)
  • Packaging2MG
  • Price₹8151.23
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) A9041 Arg-Gly-Asp-Ser ≥95% (HPLC) 10MG ₹27019.2 2022-06-14 Buy
Sigma-Aldrich(India) 03-34-0002 H-Arg-Gly-Asp-Ser-OH - CAS 91037-65-9 - Calbiochem 25MG ₹18980 2022-06-14 Buy
Sigma-Aldrich(India) A9041 Arg-Gly-Asp-Ser ≥95% (HPLC) 5MG ₹14743.65 2022-06-14 Buy
Sigma-Aldrich(India) A9041 Arg-Gly-Asp-Ser ≥95% (HPLC) 2MG ₹8151.23 2022-06-14 Buy

Properties

Melting point :183-187℃
Density :1.65±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :≥21.65 mg/mL in H2O; insoluble in EtOH; insoluble in DMSO
form :White to off-white powder
pka :2.84±0.10(Predicted)
color :White to off-white
Water Solubility :Soluble in water at 1mg/ml
Sequence :H-Arg-Gly-Asp-Ser-OH

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Fibronectin is an extracellular matrix protein which binds other proteins and interacts with cells, serving roles in cell adhesion, migration, and signaling. Like vitronectin and collagen, fibronectin contains a conserved tripeptide sequence, Arg-Gly-Asp (RGD) to associate with integrins on the cell surface. RGDS peptide is a tetrapeptide found on fibronectin, fibrinogen α, and von Willebrand factor, but not vitronectin or collagen. RGDS interacts with α5β1 and αVβ3 integrins. This tetrapeptide interferes with the attachment of cells to fibronectin-coated surfaces (Ki = 0.6 mM). It also blocks the attachment of certain pathogens to cells. RGDS peptide inhibits thrombin-induced binding of platelets to fibronectin, fibrinogen α, and von Willebrand factor (IC50 = ~10 μM). The interaction of RGDS peptide with cell surface integrins alters intracellular signaling in ways that are cell- and stimulus-specific.

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