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ARS-1620

ARS-1620 Structure
  • ₹0
  • Product name: ARS-1620
  • CAS: 1698055-85-4
  • MF: C21H17ClF2N4O2
  • MW: 430.84
  • EINECS:-0
  • MDL Number:MFCD31619312
  • Synonyms:ARS-1620;CPD1588;ARS-1620;ARS 1620;ARS1620;(S)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one ;1-?[4-?[(7S)?-?6-?Chloro-?8-?fluoro-?7-?(2-?fluoro-?6-?hydroxyphenyl)?-?4-?quinazolinyl]?-?1-?piperazinyl]?-?2-?propen-?1-?one;2-Propen-1-one, 1-[4-[(7S)-6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl]-;(S)-1-[4-[6-Chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl]-2-propen-1-one;inhibit,Ras,Inhibitor,ARS-1620,ARS 1620,ARS1620
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Boiling point :614.7±55.0 °C(Predicted)
Density :1.434±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:70.0(Max Conc. mg/mL);162.47(Max Conc. mM)
form :A solid
pka :6.03±0.35(Predicted)
color :Off-white to light yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

ARS-1620, is an atropisomeric selective KRASG12C inhibitor with desirable pharmacokinetics.