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ChemicalBook > Product Catalogue >API >Vitamins and Minerals medicines >Vitamins AD drugs >Alfacalcidol

Alfacalcidol

Alfacalcidol Structure
  • ₹7200 - ₹25611.95
  • Product name: Alfacalcidol
  • CAS: 41294-56-8
  • MF: C27H44O2
  • MW: 400.64
  • EINECS:255-297-1
  • MDL Number:MFCD00868328
  • Synonyms:5-[2E-[(3aS)-1R-[1R,5-dimethylhexyl]octahydro-7aR-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1R,3R-cyclohexanediol;Alfacalcidol/1α-Hydroxyvitamin D3;Alfacalcidol / 1α-Hydroxycholecalciferol;Vitamin D?, 1α-Hydroxy- ;7,10(19)-triene-1,3-diol,(1-alpha,3-beta,5z,7e)-10-secocholesta-5 ;ALFACALCIDOL;1-HYDROXYCHOLECALCIFEROL;1ALPHA-OH-D3
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Brand

  • Sigma-Aldrich
  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 1MG
  • 10MG
  • 50MG
  • ManufacturerSigma-Aldrich
  • Product number17946
  • Product description1α-Hydroxyvitamin D3 ≥97.0% (HPLC)
  • Packaging1MG
  • Price₹25611.95
  • Updated2022-06-14
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberA3125
  • Product descriptionAlfacalcidol
  • Packaging10MG
  • Price₹7200
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberA3125
  • Product descriptionAlfacalcidol
  • Packaging50MG
  • Price₹17000
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number17946
  • Product description1α-Hydroxyvitamin D3 ≥97.0% (HPLC)
  • Packaging1MG
  • Price₹25611.95
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich 17946 1α-Hydroxyvitamin D3 ≥97.0% (HPLC) 1MG ₹25611.95 2022-06-14 Buy
TCI Chemicals (India) A3125 Alfacalcidol 10MG ₹7200 2022-05-26 Buy
TCI Chemicals (India) A3125 Alfacalcidol 50MG ₹17000 2022-05-26 Buy
Sigma-Aldrich(India) 17946 1α-Hydroxyvitamin D3 ≥97.0% (HPLC) 1MG ₹25611.95 2022-06-14 Buy

Properties

Melting point :134-136°C
Boiling point :531.5±50.0 °C(Predicted)
Density :1.01±0.1 g/cm3(Predicted)
storage temp. :−20°C
solubility :Practically insoluble in water, freely soluble in ethanol (96 per cent), soluble in fatty oils.
form :White crystalline solid
pka :14.43±0.40(Predicted)
color :White to Almost white
λmax :264nm(Diethyl ether)(lit.)
Merck :14,4819
Stability :Light Sensitive
InChIKey :OFHCOWSQAMBJIW-GITLSTMWSA-N
SMILES :[C@@H]1(O)CC(=C/C=C2\CCC[C@@]3(C)[C@@]\2([H])CC[C@@H]3[C@H](C)CCCC(C)C)C(=C)[C@H](O)C1
CAS DataBase Reference :41294-56-8(CAS DataBase Reference)
EPA Substance Registry System :Alphacalcidol (41294-56-8)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:

Description

Vitamin D aids in the absorption of calcium and has central roles in bone formation and maintenance, hypertension, cancer, and immunity. 1-hydroxy Vitamin D3 is a synthetic prodrug which is converted by cytochrome P450 isoforms to the vitamin D receptor agonist 1,25-dihydroxy vitamin D3 in vivo. Such prodrugs are effective in suppressing the synthesis and secretion of parathyroid hormone in secondary hyperparathyroidism, an action which requires the vitamin D receptor. 1-hydroxy Vitamin D3 supports bone growth both in postmenopausal women and in glucocorticoid-induced osteoporosis. It also provides renal and cardiovascular protection during chronic kidney disease.

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