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ChemicalBook > Product Catalogue >API >Respiratory Drugs >Expectorants >Ambroxol

Ambroxol

Ambroxol Structure
  • ₹0
  • Product name: Ambroxol
  • CAS: 18683-91-5
  • MF: C13H18Br2N2O
  • MW: 378.1
  • EINECS:242-500-3
  • MDL Number:MFCD00242702
  • Synonyms:4-((2-amino-3,5-dibromobenzyl)amino)-(e)-cyclohexano ;5-dibromophenyl)methyl)amino)-4-(((2-amino-trans-cyclohexano ;Cyclohexanol, 4-((2-amino-3,5-dibromobenzyl)amino)- (E)-;Cyclohexanol, 4-[[(2-amino-3,5-dibromophenyl)methyl]amino]-, trans-;n-(2-amino-3,4-dibromociclohexil)-trans-4-aminociclohexanol ;n-(2-amino-3,4-dibromocyclohexyl)-trans-4-aminocyclohexanol ;N-(trans-4-Hidroxiciclohexil)-(2-amino-3,5-dibromobencil)amina;N-(trans-4-Hydroxycyclohexyl)-(2-amino-3,5-dibromobenzyl)-amine
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :233-234 C
Boiling point :468.6±45.0 °C(Predicted)
Density :1.5863 (rough estimate)
refractive index :1.6220 (estimate)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :Soluble in Water.
form :solid
pka :15.12±0.40(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.
CAS DataBase Reference :18683-91-5(CAS DataBase Reference)
NIST Chemistry Reference :Ambroxol(18683-91-5)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P501 Dispose of contents/container to..…

Description

Ambroxol HCl (18683-91-5) is a radical scavenger with anti-inflammatory activity. Blocks the generation of reactive oxygen species by bronchoalveolar lavage cells, inhibits doxorubicin-induced lipid peroxidation (70 mg/kg in rat), and inhibits the release of inflammatory mediators from human leukocytes and mast cells (effective dose ~ 100 μM)

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