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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Immunosuppressants >Azathioprine

Azathioprine

Azathioprine Structure
  • ₹8042.98 - ₹14200
  • Product name: Azathioprine
  • CAS: 446-86-6
  • MF: C9H7N7O2S
  • MW: 277.26
  • EINECS:207-175-4
  • MDL Number:MFCD00069203
  • Synonyms:6-((1-methyl-4-nitro-1h-imidazol-5-yl)thio)-1h-purin ;6-((1-methyl-4-nitroimidazol-5-yl)thio)-purin ;6-(1’-methyl-4’-nitro-5’-imidazolyl)-mercaptopurine ;6-(1-Methyl-4-nitro-5-imidazolythio)-9H-pur-ine ;6-(1-methyl-4-nitroimidazol-5-ylthio)purin ;6-(1-methyl-p-nitro-5-imidazolyl)-thiopurine ;Azathioprine (200 mg);USP30/EP5 API
Price4 Properties Safety Information Description
4 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 1G
  • 5G
  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberA2069
  • Product descriptionAzathioprine
  • Packaging5G
  • Price₹10300
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberA2069
  • Product descriptionAzathioprine
  • Packaging25G
  • Price₹14200
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1282
  • Product descriptionAzathioprine Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹8042.98
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA4638
  • Product descriptionAzathioprine ≥98%
  • Packaging1G
  • Price₹10446.13
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) A2069 Azathioprine 5G ₹10300 2022-05-26 Buy
TCI Chemicals (India) A2069 Azathioprine 25G ₹14200 2022-05-26 Buy
Sigma-Aldrich(India) PHR1282 Azathioprine Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹8042.98 2022-06-14 Buy
Sigma-Aldrich(India) A4638 Azathioprine ≥98% 1G ₹10446.13 2022-06-14 Buy

Properties

Melting point :243-244°C
Boiling point :521.0±60.0 °C(Predicted)
Density :1.5379 (rough estimate)
refractive index :1.7400 (estimate)
storage temp. :2-8°C
solubility :Soluble in Dichloromethane and dimethyl sulfoxide.
pka :8.2(at 25℃)
form :Solid
color :Pale-yellow crystals from Me2CO (aq)
Water Solubility :<0.1 g/100 mL at 23 ºC
Merck :14,902
BCS Class :4
Stability :Stable. Incompatible with strong oxidizing agents, strong bases.
InChIKey :LMEKQMALGUDUQG-UHFFFAOYSA-N
CAS DataBase Reference :446-86-6(CAS DataBase Reference)
IARC :1 (Vol. 26, Sup 7, 100A) 2012
EPA Substance Registry System :Azathioprine (446-86-6)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H350 May cause cancer Carcinogenicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Azathioprine is a purine analog with immunosuppressive effects. It serves as a prodrug for 6-mercaptopurine, which alters purine processing and DNA synthesis, interfering with the proliferation of lymphocytes and other myeloid cells. Its immunomodulating actions are used to benefit inflammatory bowel disease, as well as a wide range of additional diseases with immunological or autoimmunological components, including rheumatoid arthritis and lupus nephritis.

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Suppliers and manufacturers

AARTI INDUSTRIES LIMITED Jigs Chemical ltd Micro Orgo Chem Flax Laboratories Rivashaa Agrotech Biopharma Pvt. Ltd. Zydus Lifesciences Ltd. Besil Chem LLP Humble Healthcare Limited Aarti Industries Limited (AIL) Ralington Pharma