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ChemicalBook > Product Catalogue >API >Synthetic Anti-infective Drugs >Antifungal Drugs >BAFILOMYCIN A1

BAFILOMYCIN A1

BAFILOMYCIN A1 Structure
  • ₹10359.53 - ₹44200.01
  • Product name: BAFILOMYCIN A1
  • CAS: 88899-55-2
  • MF: C35H58O9
  • MW: 622.83
  • EINECS:621-324-4
  • MDL Number:MFCD06795130
  • Synonyms:Bafilomycin A1 Bafilomycin A1 from Streptomyces griseus;Bafilomycin A1(Baf-A1);BAFILOMYCIN A1;BAFILOMYCIN A1, STREPTOMYCES GRISEUS;BAFILOMYCIN A1, 98+%;BAFILOMYCIN A1 95%;(3Z,5E,7R,8S,9S,11E,13E,15S,16R)-8-Hydroxy-16-((1S,2R,3S)-2-hydroxy-1-methyl-3-((2R,4R,5S,6R)-tetrahydro-2,4-dihydroxy-5;BafilomycinA1fromStreptomycesgriseus
5 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 10μG
  • 0.1ML
  • 1SET
  • 2μG
  • ManufacturerSigma-Aldrich(India)
  • Product numberB1793
  • Product descriptionBafilomycin A1 from Streptomyces griseus ≥90% (HPLC)
  • Packaging2μG
  • Price₹10359.53
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1661
  • Product descriptionBafilomycin A1 Ready Made Solution 0.16?mM in DMSO, from Streptomyces griseus
  • Packaging0.1ML
  • Price₹18713.1
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number196000
  • Product descriptionBafilomycin A1, Streptomyces griseus - CAS 88899-55-2 - Calbiochem Bafilomycin A1, CAS 88899-55-2, acts as a highly potent and specific inhibitor of vacuolar-type H+-ATPase (Ki = 500 pM). Blocks the fusion of autophag
  • Packaging10μG
  • Price₹21130
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberB1793
  • Product descriptionBafilomycin A1 from Streptomyces griseus ≥90% (HPLC)
  • Packaging10μG
  • Price₹27322.3
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number196000
  • Product descriptionBafilomycin A1, Streptomyces griseus - CAS 88899-55-2 - Calbiochem Bafilomycin A1, CAS 88899-55-2, acts as a highly potent and specific inhibitor of vacuolar-type H+-ATPase (Ki = 500 pM). Blocks the fusion of autophag
  • Packaging1SET
  • Price₹44200.01
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) B1793 Bafilomycin A1 from Streptomyces griseus ≥90% (HPLC) 2μG ₹10359.53 2022-06-14 Buy
Sigma-Aldrich(India) SML1661 Bafilomycin A1 Ready Made Solution 0.16?mM in DMSO, from Streptomyces griseus 0.1ML ₹18713.1 2022-06-14 Buy
Sigma-Aldrich(India) 196000 Bafilomycin A1, Streptomyces griseus - CAS 88899-55-2 - Calbiochem Bafilomycin A1, CAS 88899-55-2, acts as a highly potent and specific inhibitor of vacuolar-type H+-ATPase (Ki = 500 pM). Blocks the fusion of autophag 10μG ₹21130 2022-06-14 Buy
Sigma-Aldrich(India) B1793 Bafilomycin A1 from Streptomyces griseus ≥90% (HPLC) 10μG ₹27322.3 2022-06-14 Buy
Sigma-Aldrich(India) 196000 Bafilomycin A1, Streptomyces griseus - CAS 88899-55-2 - Calbiochem Bafilomycin A1, CAS 88899-55-2, acts as a highly potent and specific inhibitor of vacuolar-type H+-ATPase (Ki = 500 pM). Blocks the fusion of autophag 1SET ₹44200.01 2022-06-14 Buy

Properties

Melting point :>106°C (dec.)
Boiling point :582.86°C (rough estimate)
Density :1.0594 (rough estimate)
refractive index :1.5000 (estimate)
RTECS :RN9781000
Flash point :87℃
storage temp. :-20°C
solubility :Soluble in DMSO (up to 5 mg/ml, with warming).
pka :12.66±0.70(Predicted)
form :Powder or Solid
color :White to off-white
Water Solubility :Soluble in methanol, ethanol, acetone and chloroform. Insoluble in water.
BRN :4730700
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H227 Combustible liquid Flammable liquids Category 4 Warning P210, P280, P370+P378, P403+P235,P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P403+P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.

Description

Bafilomycin A1 is a selective, reversible inhibitor of vacuolar H+-ATPases (V-ATPases), blocking these proton pumps in mammalian, plant, or fungal cells with an IC50 value in the 4-400 nM range. It is at least 1,000-fold less potent at most other types of ATPases. Bafilomycin A1 also inhibits autophagy by preventing vacuolar acidification necessary for autophagosome maturation.

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