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BICALUTAMIDE-D4

BICALUTAMIDE-D4 Structure
  • ₹0
  • Product name: BICALUTAMIDE-D4
  • CAS: 1185035-71-5
  • MF: C18H14F4N2O4S
  • MW: 430.37
  • EINECS:
  • MDL Number:MFCD08063408
  • Synonyms:BICALUTAMIDE-D4;Casodex-d4;ICI-176334-d4;N-[4-Cyano-3-trifluoromethyl)phenyl]- 3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide-d4;(CI-176334-D4;Bicalutamide Impurity 17;[2H4]-Bicalutamide
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :192-1940C
storage temp. :-20°C Freezer
solubility :Chloroform (Slightly, Heated), Methanol (Slightly, Sonicated)
form :Solid
color :White to Off-White

Safety Information

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Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
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Description

Bicalutamide-d4 is intended for use as an internal standard for the quantification of bicalutamide by GC- or LC-MS. Bicalutamide is a non-steroidal androgen receptor antagonist that binds the androgen receptor (Ki = 12.5 μM; IC50 = 1.2 μM), preventing its activation and subsequent upregulation of androgen responsive genes by androgenic hormones. Bicalutamide is frequently used to examine the role of androgen receptor inactivation in the proliferation of prostate cancer cells and has served as a molecular template for the design and structural optimization of more selective androgen receptor modulators for androgen therapy.

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