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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Metabolism >Carbonic Anhydrase Inhibitors >Brinzolamide

Brinzolamide

Brinzolamide Structure
  • ₹4900 - ₹52133.2
  • Product name: Brinzolamide
  • CAS: 138890-62-7
  • MF: C12H21N3O5S3
  • MW: 383.51
  • EINECS:620-511-8
  • MDL Number:MFCD08067749
  • Synonyms:H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide, 4-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-, 1,1-dioxide, (4R)-;Brinzolamide (R)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide;(5R)-5-Ethylamino-3-(3-methoxypropyl)-2,2-dioxo-2?6,9-dithia-3-azabicyclo[4.3.0]nona-7,10-diene-8-sulfonamide;ANTI-GAGE7 (C-TERM) antibody produced in rabbit;Cancer/testis antigen 4.7;CT4.7;G antigen 7;GAGE-12I
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 25MG
  • 50MG
  • 100MG
  • ManufacturerTCI Chemicals (India)
  • Product numberB4258
  • Product descriptionBrinzolamide
  • Packaging25MG
  • Price₹4900
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberB4258
  • Product descriptionBrinzolamide
  • Packaging100MG
  • Price₹9200
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0216
  • Product descriptionBrinzolamide ≥98% (HPLC)
  • Packaging10MG
  • Price₹12979.18
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0216
  • Product descriptionBrinzolamide ≥98% (HPLC)
  • Packaging50MG
  • Price₹52133.2
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) B4258 Brinzolamide 25MG ₹4900 2022-05-26 Buy
TCI Chemicals (India) B4258 Brinzolamide 100MG ₹9200 2022-05-26 Buy
Sigma-Aldrich(India) SML0216 Brinzolamide ≥98% (HPLC) 10MG ₹12979.18 2022-06-14 Buy
Sigma-Aldrich(India) SML0216 Brinzolamide ≥98% (HPLC) 50MG ₹52133.2 2022-06-14 Buy

Properties

Melting point :130.0 to 134.0 °C
Boiling point :586.0±60.0 °C(Predicted)
Density :1.50±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: ≥10mg/mL
pka :9.62±0.40(Predicted)
form :powder
color :white to beige
Merck :14,1376
InChIKey :HCRKCZRJWPKOAR-JTQLQIEISA-N
CAS DataBase Reference :138890-62-7(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P501 Dispose of contents/container to..…

Description

Brinzolamide is a carbonic anhydrase inhibitor developed by Alcon (now Novartis) as a treatment for primary and open-angle glaucoma and ocular hypertension. It was First approval in the United States in 1998 under the trade name Azopt. It is the second of this class after dorzolamide (1995). Brinzolamide was approved as a generic medication in the United States in November 2020.Brinzolamide is a white powder commercially formulated as a 1% ophthalmic suspension to reduce intraocular pressure (IOP). In patients with primary open-angle glaucoma or ocular hypertension, brinzolamide produced significant reductions in IOP and showed less ocular discomfort than dorzolamide.

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