Brinzolamide-d5
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- ₹0
- Product name: Brinzolamide-d5
- CAS: 1217651-02-9
- MF: C12H21N3O5S3
- MW: 383.5
- EINECS:
- MDL Number:
- Synonyms:[2H5]-Brinzolamide;Brinzolamide-d5
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Properties
storage temp. :Refrigerator
solubility :Ethanol
form :Solid
color :Crystalline
solubility :Ethanol
form :Solid
color :Crystalline
Safety Information
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Signal word: | Warning | |||||||
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Description
Brinzolamide-d5 is intended for use as an internal standard for the quantification of brinzolamide by GC- or LC-MS. Brinzolamide is a potent inhibitor of carbonic anhydrase II (CAII) and CAIV (IC50s = 3.19 and 45.3 nM, respectively). It is selective for CAII and CAIV over CAI (IC50 = ~1,365 nM). Brinzolamide (30 mg/kg) reduces intestinal charcoal meal progression by 44% and prolongs pentobarbital sodium-induced sleep time by 35% in mice. Topical administration of brinzolamide (0.25, 0.5, and 1 mg/eye) reduces intraocular pressure in a rabbit model of spontaneous ocular hypertension. It also reduces intraocular pressure in a cynomolgus monkey model of argon laser trabeculoplasty-induced ocular hypertension. Formulations containing brinzolamide have been used in the treatment of glaucoma and ocular hypertension.Related product price
- Dilthiazem hydrochloride
₹3311.7-74551.78 - Brinzolamide
₹4900-52133.2
Suppliers and manufacturers
CLEARSYNTH LABS LTD.
Pharmaffiliates Analytics and Synthetics P. Ltd
SynZeal Research Pvt Ltd
Pharma Affiliates
Shanghai Hao Zhun Biological Technology Co., Ltd.
Shanghai isotope chemical co.,ltd
Cayman Chemical Company
Shanghai EFE Biological Technology Co., Ltd.
Hubei Yangxin Medical Technology Co., Ltd.
Nanjing Shizhou Biology Technology Co.,Ltd