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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Endocrinology & Hormones >RAAS inhibitors >ENALAPRILAT DIHYDRATE

ENALAPRILAT DIHYDRATE

ENALAPRILAT DIHYDRATE Structure
  • ₹14516.33 - ₹54926.05
  • Product name: ENALAPRILAT DIHYDRATE
  • CAS: 84680-54-6
  • MF: C18H26N2O6
  • MW: 366.41
  • EINECS:689-724-1
  • MDL Number:MFCD00941393
  • Synonyms:(S)-1-[N-[1-(CARBOXY)-3-PHENYLPROPYL]-L-ALANYL]-L-PROLINE, DIHYDRATE;MK-422;ENALAPRILAT DIHYDRATE;ENALAPRILATE;Enalaprilate USP25;ENALAPRILAT USP;Enalaprilat (300 mg);Enalaprilic Acid Dihydrate
3 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • 250MG
  • ManufacturerTCI Chemicals (India)
  • Product numberE1302
  • Product descriptionEnalaprilat Dihydrate
  • Packaging250MG
  • Price₹18700
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberE9658
  • Product descriptionEnalaprilat dihydrate ≥98% (HPLC)
  • Packaging5MG
  • Price₹14516.33
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberE9658
  • Product descriptionEnalaprilat dihydrate ≥98% (HPLC)
  • Packaging25MG
  • Price₹54926.05
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) E1302 Enalaprilat Dihydrate 250MG ₹18700 2022-05-26 Buy
Sigma-Aldrich(India) E9658 Enalaprilat dihydrate ≥98% (HPLC) 5MG ₹14516.33 2022-06-14 Buy
Sigma-Aldrich(India) E9658 Enalaprilat dihydrate ≥98% (HPLC) 25MG ₹54926.05 2022-06-14 Buy

Properties

Melting point :151-159°C
alpha :[α]D25 -53.0~-56.0゜ (c=1, CH3OH) (Calculated on dehydrous basis)
storage temp. :2-8°C
solubility :H2O: soluble14mg/mL at 60°C (warming for 5 minutes)
form :Solid
color :White to Off-White
CAS DataBase Reference :84680-54-6(CAS DataBase Reference)
EPA Substance Registry System :L-Proline, N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-, hydrate (1:2) (84680-54-6)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Angiotensin-converting enzyme (ACE) converts angiotensin I to angiotensin II, a peptide hormone that impacts vascular smooth muscle tone and renal salt exchange, driving hypertension. Enalaprilat is the active metabolite of enalapril , an ACE inhibitor with roles in the management of hypertension, congestive heart failure, myocardial infarction, and diabetic nephropathies.. Enalaprilat is esterified with ethanol to produce enalapril in order to enable oral activity and subsequently metabolized in vivo to the active form by various esterases. Enalaprilat is reported to inhibit ACE activity with an IC50 value of 5.8 nM in vitro.

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