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ChemicalBook > Product Catalogue >API >Circulatory system drugs >Antihypertensive drugs >Enalaprilat

Enalaprilat

Enalaprilat Structure
  • ₹12513.7
  • Product name: Enalaprilat
  • CAS: 76420-72-9
  • MF: C18H24N2O5
  • MW: 348.39
  • EINECS:278-459-3
  • MDL Number:MFCD00865786
  • Synonyms:ENALAPRILAT HYDRATE;ENALAPRILAT USP(CRM STANDARD);Enalapril acid;L-Proline, 1-[N-(1-carboxy-3-phenylpropyl)-L-alanyl]-, (S)-;N-[1(S)-Carboxy-3-phenylpropyl]-L-alanyl-L-proline;1-[N-[(S)-1-Carboxy-3-phenylpropyl]-L-alanyl]-L-proline;Enalapril diacid;(2S)-1-[(2S)-2-{[(2R)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]aMino}propanoyl]pyrrolidine-2-carboxylic acid
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Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product number43301
  • Product descriptionEnalaprilat analytical standard
  • Packaging25MG
  • Price₹12513.7
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 43301 Enalaprilat analytical standard 25MG ₹12513.7 2022-06-14 Buy

Properties

Melting point :148-151°C
alpha :D -67.0° (0.1M HCl)
Boiling point :601.0±55.0 °C(Predicted)
Density :1.286±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Very slightly soluble or slightly soluble in water, sparingly soluble in methanol, practically insoluble in acetonitrile.
pka :pKa 2.30 (Uncertain);3.39 (Uncertain)
Water Solubility :Soluble in water with heating (~60°C)
CAS DataBase Reference :76420-72-9(CAS DataBase Reference)
EPA Substance Registry System :L-Proline, N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl- (76420-72-9)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

Enalapril is a ACE (angiotensin-converting enzyme) inhibitor, suggested to be more potent than Captopril (sc-200566). Studies indicate that Enalapril downregulates the expression of IL-β, IL-6, and NF-κB. Further studies show that Enalapril upregulates the expression of VEGF and heme oxygenase-1. Enalaprilat reports demonstrate that the compound has some antioxidant activity, which does not include the PKC-NADPH oxidase pathway.

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