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ChemicalBook > Product Catalogue >API >Circulatory system drugs >Angina Pectoris Drugs >Nifedipine

Nifedipine

Nifedipine Structure
  • ₹6200 - ₹52988.38
  • Product name: Nifedipine
  • CAS: 21829-25-4
  • MF: C17H18N2O6
  • MW: 346.33
  • EINECS:244-598-3
  • MDL Number:MFCD00057326
  • Synonyms:1,4-Dihydro-2,6-dimethyl-4-(o-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl;Nifedipine,1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester;Nifedipine (125 mg);Niter benzene horizontal;1,4-dihydro-2,6-diMethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylate;ALDIPIN ANIFED;ADALATE;4-(2'-NITROPHENYL)-2,6-DIMETHYL-3,5-DICARBOMETHOXY-1,4-DIHYDROPYRIDINE
8 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 250MG
  • 1G
  • 5G
  • 10G
  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberN0528
  • Product descriptionNifedipine
  • Packaging10G
  • Price₹6200
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberN0528
  • Product descriptionNifedipine
  • Packaging25G
  • Price₹10500
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number481981
  • Product descriptionNifedipine - CAS 21829-25-4 - Calbiochem Relatively selective blocker of L-type Ca2+ channels.
  • Packaging250MG
  • Price₹6860
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberN7634
  • Product descriptionNifedipine ≥98% (HPLC), powder
  • Packaging1G
  • Price₹7263.58
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1290
  • Product descriptionNifedipine Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹7664.1
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberN7634
  • Product descriptionNifedipine ≥98% (HPLC), powder
  • Packaging5G
  • Price₹19528.3
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberN7634
  • Product descriptionNifedipine ≥98% (HPLC), powder
  • Packaging10G
  • Price₹29920.3
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberN7634
  • Product descriptionNifedipine ≥98% (HPLC), powder
  • Packaging25G
  • Price₹52988.38
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) N0528 Nifedipine 10G ₹6200 2022-05-26 Buy
TCI Chemicals (India) N0528 Nifedipine 25G ₹10500 2022-05-26 Buy
Sigma-Aldrich(India) 481981 Nifedipine - CAS 21829-25-4 - Calbiochem Relatively selective blocker of L-type Ca2+ channels. 250MG ₹6860 2022-06-14 Buy
Sigma-Aldrich(India) N7634 Nifedipine ≥98% (HPLC), powder 1G ₹7263.58 2022-06-14 Buy
Sigma-Aldrich(India) PHR1290 Nifedipine Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹7664.1 2022-06-14 Buy
Sigma-Aldrich(India) N7634 Nifedipine ≥98% (HPLC), powder 5G ₹19528.3 2022-06-14 Buy
Sigma-Aldrich(India) N7634 Nifedipine ≥98% (HPLC), powder 10G ₹29920.3 2022-06-14 Buy
Sigma-Aldrich(India) N7634 Nifedipine ≥98% (HPLC), powder 25G ₹52988.38 2022-06-14 Buy

Properties

Melting point :171-175 °C
Boiling point :481.08°C (rough estimate)
Density :1.2109 (rough estimate)
refractive index :1.5486 (estimate)
storage temp. :2-8°C
solubility :DMSO: soluble
form :powder
pka :pKa -0.9/>13(DMF,t undefined) (Uncertain)
color :yellow
Water Solubility :<0.1 g/100 mL at 19.5 ºC
Merck :14,6528
BCS Class :2
Stability :Stable for 1 year from date of purchase as supplied. Solutions are not stable and must be used within one working day.
InChIKey :CYCWGQFQPAYBHG-UHFFFAOYSA-N
CAS DataBase Reference :21829-25-4(CAS DataBase Reference)
NIST Chemistry Reference :Nifedipine(21829-25-4)
EPA Substance Registry System :Dimethyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylate (21829-25-4)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:

Description

Nifedipine is a dihydropyridine calcium channel blocker widely used as a coronary vasodilator for the treatment of hypertension and angina. Aside from its hypotensive effects, nifedipine exhibits cardiac organ-protective effects, ameliorates endothelial dysfunctions through an anti-apoptotic effect, displays antioxidant activity, reduces gastric acid secretion, has been used as a tocolytic agent to delay preterm labor, reduces the number of Raynaud’s phenomenon attacks, and has proved effective in addressing high-altitude pulmonary edema.

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