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ChemicalBook > Product Catalogue >API >Circulatory system drugs >Antihypertensive drugs >Enalapril

Enalapril

Enalapril Structure
  • ₹0
  • Product name: Enalapril
  • CAS: 75847-73-3
  • MF: C20H28N2O5
  • MW: 376.45
  • EINECS:
  • MDL Number:MFCD00865774
  • Synonyms:ENALAPRIL;(s)-1-(n-(1-(ethoxycarbonyl)-3-phenylpropyl)-l-alanyl)-l-proline;1-(n-((s)-1-carboxy-3-phenylpropyl)-l-alanyl)-l-proline 1'-ethyl ester;1-[2-(1-ETHOXYCARBONYL-3-PHENYL-PROPYL)AMINOPROPANOYL]PYRROLIDINE-2-CARBOXYLIC ACID;Renitec;Enalapril Maleate USP24;L-Proline, 1-[N-[1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl]-, (S)-;L-Proline, N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :142-147℃
Boiling point :582.4±50.0 °C(Predicted)
Density :1.204±0.06 g/cm3(Predicted)
RTECS :TW3665500
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :Soluble in DMSO
form :Powder
pka :pKa 2.97 (H2O t=25.0)(Approximate);5.35(H2O t=25.0)(Approximate)
Water Solubility :Soluble in water at 25mg/ml
BCS Class :3
CAS DataBase Reference :75847-73-3(CAS DataBase Reference)
EPA Substance Registry System :L-Proline, N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl- (75847-73-3)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Angiotensin-converting enzyme converts angiotensin I to angiotensin II, a peptide hormone that impacts vascular smooth muscle tone and renal salt exchange, driving hypertension. Enalapril is an orally-active ACE inhibitor (IC50 values range from 2 to 800 nM). It has roles in the management of hypertension, congestive heart failure, myocardial infarction, and diabetic nephropathies.

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Ethylparaben Ethylbenzene Ethyl acrylate cis-4-Hydroxy-L-proline Ethyl acetate Etanol 10497-05-9 D-Pyrrolidine-2-carboxylic acid ENALAPRILAT-D5, SODIUM SALT Trandolapril Enalapril maleate Diethyl ether Ramipril 82717-96-2 84793-24-8 Enalaprilat 2-Pyrrolidinecarboxylic acid

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Suppliers and manufacturers

J S LABS Varanous Labs Pvt Ltd SG Pharma Pvt Ltd Vijaya Pharma And Life Science Gansai International KPS Chemicals & Pharmaceuticals Pharma Affiliates J. C. Enterprises Pharmaffiliates Analytics & Synthetics (P) Ltd. Refsyn Biosciences Pvt., Ltd.