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ChemicalBook > Product Catalogue >API >Circulatory system drugs >Antihypertensive drugs >Ramipril

Ramipril

Ramipril Structure
  • ₹7000 - ₹46893.9
  • Product name: Ramipril
  • CAS: 87333-19-5
  • MF: C23H32N2O5
  • MW: 416.51
  • EINECS:642-904-3
  • MDL Number:MFCD00865775
  • Synonyms:Ramioril;(2S,3AS,6AS)-1-((S)-2-((S)-1-ETHOXY-1-OXO-4-PHENYLBUTAN-2-YLAMINO)PROPANOYL)-OCTAHYDROCYCLOPENTA[B]PYRROLE-2-CARBOXYLIC ACID;Triatec;Trimce;vesdil;(1S,5S,7S)-8-[(2S)-2-[[(1S)-1-Ethoxycarbonyl-3-phenyl-propyl]amino]propanoyl]-8-azabicyclo[3.3.0]octane-7-carboxylic acid;Cyclopenta(b)pyrrole-2-carboxylic acid, octahydro-1-(2-((1-(ethoxycarbonyl)-3-phenylpropyl) amino)-1-oxopropyl), (2S-(1(R*(R*)),2-alpha,3a-beta,6a-beta));4-[2-(1-Ethoxycarbonyl-3-phenyl-propyl)aminopropanoyl]-4-azabicyclo[3.3.0]octane-3-carboxylic acid
Price5 Properties Safety Information Description
5 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)
  • TCI Chemicals (India)

Package

  • 100MG
  • 250MG
  • 1G
  • 5G
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1446
  • Product descriptionRamipril Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹9926.53
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberR0404
  • Product descriptionRamipril ≥98% (HPLC)
  • Packaging100MG
  • Price₹23111.38
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberR0404
  • Product descriptionRamipril ≥98% (HPLC)
  • Packaging250MG
  • Price₹46893.9
  • Updated2022-06-14
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberR0219
  • Product descriptionRamipril
  • Packaging5G
  • Price₹14200
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberR0219
  • Product descriptionRamipril
  • Packaging1G
  • Price₹7000
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) PHR1446 Ramipril Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹9926.53 2022-06-14 Buy
Sigma-Aldrich(India) R0404 Ramipril ≥98% (HPLC) 100MG ₹23111.38 2022-06-14 Buy
Sigma-Aldrich(India) R0404 Ramipril ≥98% (HPLC) 250MG ₹46893.9 2022-06-14 Buy
TCI Chemicals (India) R0219 Ramipril 5G ₹14200 2022-05-26 Buy
TCI Chemicals (India) R0219 Ramipril 1G ₹7000 2022-05-26 Buy

Properties

Melting point :106-108°C
Boiling point :616.2±55.0 °C(Predicted)
alpha :D24 +33.2° (c = 1 in 0.1N ethanolic HCl)
Density :1.200±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ~18mg/mL
pka :pKa 3.30±0.01(H2O t = 25.0 I = 0.15 (KCl)) (Uncertain);5.75±0.00(H2O t = 25.0 I = 0.15 (KCl)) (Uncertain)
form :powder
color :white
BCS Class :1
CAS DataBase Reference :87333-19-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Ramipril (brand name: Altace) is a kind of prodrug which is capable of inhibiting the angiotensin-converting enzyme (ACE) which converting angiotensin I to angiotensin II. It is metabolized to ramiprilat in the liver which exerts the effect of ACE inhibition. It is used for the treatment of hypertension, congestive heart failure and nephropathy. It can also be used for the prevention of heart attack, stroke and cardiovascular death. It can also be used for the treatment of kidney damage due to diabetes with protein-containing urine. Ramiprilat, is the competitive inhibitor of ATI for binding to ACE, further inhibiting the enzymatic proteolysis of ATI to ATII, alleviating the effect of ATII on blood pressure.

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Suppliers and manufacturers

AARTI INDUSTRIES LIMITED Dr. Reddy's Laboratories Ltd AnalyticsStanza Inc S.V ENTERPRISES Varanous Labs Pvt Ltd Cipla Ltd Aarti Industries Limited (AIL) Hetero Drugs Limited MELODY HEALTHCARE PVT LTD HRV Global Life Sciences