Balofloxacin
|
- ₹0
- Product name: Balofloxacin
- CAS: 127294-70-6
- MF: C20H24FN3O4
- MW: 389.42
- EINECS:1312995-182-4
- MDL Number:MFCD00864925
- Synonyms:3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-Methoxy-7-[3-(MethylaMino)-1-piperidinyl]-4-oxo-;1-Cyclopropyl-6-fluoro-8-Methoxy-7-(3-(MethylaMino)piperidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid;1-Cyclopropyl-6-fluoro-8-methoxy-7-(3-(methylamino)piperidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-c;1-Cyclopropyl-6-fluoro-8-methoxy-7-(3-(methylamino)piperidin-1-yl)-4-oxo-1,4-dihydroquinoline-;Balofloxacin, >=99%;1-cyclopropyl-6-fluoro-1,4- dihydro-8-methoxy-7-(3-methylaminopiperidin-1-yl)-4-oxoquinoline-3-carboxylic acid;BALOFLOXACIN;3-quinolinecarboxylicacid,1,4-dihydro-1-cyclopropyl-6-fluoro-8-methoxy-7-(3-(
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|
Properties
Melting point :137°C
Boiling point :608.3±55.0 °C(Predicted)
Density :1.40±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :H2O : < 0.1 mg/mL (insoluble)DMSO : 0.67 mg/mL (1.72 mM; Need ultrasonic)
form :Solid
pka :6.44±0.50(Predicted)
color :White to off-white
BRN :8362117
CAS DataBase Reference :127294-70-6(CAS DataBase Reference)
Boiling point :608.3±55.0 °C(Predicted)
Density :1.40±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :H2O : < 0.1 mg/mL (insoluble)DMSO : 0.67 mg/mL (1.72 mM; Need ultrasonic)
form :Solid
pka :6.44±0.50(Predicted)
color :White to off-white
BRN :8362117
CAS DataBase Reference :127294-70-6(CAS DataBase Reference)
Safety Information
| Symbol(GHS): |
|
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | ||||||||||||||
| Hazard statements: |
|
||||||||||||||
| Precautionary statements: |
|
Description
Balofloxacin, a novel orally-active fluoroquinolone antibiotic, was introduced in South Korea for the treatment of urinary tract infections (UTI). It can be synthetized by reaction of 3-(methylamino)piperidine with the classical 4-quinolone-3-carboxylic acid template. In vitro antibacterial activity of balofloxacin against gram-positive bacteria (Staphylococcus aureus including methicillin-resistant S. aureus, Staphylococcus epidermis, Streptococcus pneumonia, Streptococcus pyrogenes) was almost equal to that of sparfloxacin or tosufloxacin, in contrast its activity against gram-negative bacteria was 2 times or more lower. In clinical trials, balofloxacin was well tolerated and showed comparable efficacy to ofloxacin in patients with UTls. After oral administration, balofloxacin was well absorbed, and was primarily eliminated unchanged in the urine with an elimination half-life of approximately 8 h. In animal studies, balofloxacin did not exhibit any phototoxicity.More related product prices
Anisic acid Anisole Guaiacol p-Anisaldehyde 4-Methoxyphenol p-Anisidine 4-Methoxybenzylchloride (Trifluoromethoxy)benzene Levofloxacin hydrochloride Norfloxacin Ofloxacin 4-(Trifluoromethoxy)aniline Pazufloxacin Clinafloxacin Sparfloxacin 1,1,1-Tris(4-hydroxyphenyl)ethaneRelated product price
- Anisic acid
₹297-245640.9 - Anisole
₹650-83670 - Guaiacol
₹1060-48874.88
