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ChemicalBook > Product Catalogue >API >Synthetic Anti-infective Drugs >Quinolones >Pazufloxacin

Pazufloxacin

Pazufloxacin Structure
  • ₹15717.9
  • Product name: Pazufloxacin
  • CAS: 127045-41-4
  • MF: C16H15FN2O4
  • MW: 318.3
  • EINECS:635-036-1
  • MDL Number:MFCD00865012
  • Synonyms:PAZUFLOXAXIN;T-3761;(s)-yclopropyl)-9-fluoro-3-methyl-7-oxo ;Pazufloxacinmyesylate ;(3S)-10-(1-AMINOCYCLOPROPYL)-9-FLUORO-2,3-DIHYDRO-3-METHYL-7-OXO-7H-PYRIDO[1,2,3-DE]-1,4-BENZOXAZINE-6-CARBOXYLIC ACID;ALKALYL;Pazufloxaxin mesilate ;PAZUFLOXACIN 98+%
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Brand

  • Sigma-Aldrich(India)

Package

  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product number34213
  • Product descriptionPazufloxacin VETRANAL?, analytical standard
  • Packaging25MG
  • Price₹15717.9
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 34213 Pazufloxacin VETRANAL?, analytical standard 25MG ₹15717.9 2022-06-14 Buy

Properties

Melting point :269-271°C
alpha :D25 -88.0° (c = 0.5 in 0.05N aq NaOH)
Boiling point :531.5±50.0 °C(Predicted)
Density :1.56
storage temp. :2-8°C
solubility :Aqueous Base (Slightly, Sonicated), DMSO (Slightly, Heated), Methanol (Slightly)
pka :5.05±0.40(Predicted)
color :Off-White to Pale Yellow
CAS DataBase Reference :127045-41-4(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

Description

Pazufloxacin is a fluoroquinolone with a 1-aminocyclopropyl substituent at C10 position. The presence of aminoacyl group at C-10 is a unique feature of the molecule imparting potent broad spectrum activity against gram-positive and gram-negative bacteria. This activity is based on the inhibition of bacterial DNA gyrase.
Pazufloxacin is used as an injectable antibiotic with bacterial effect against cephalosporin-resistant, carbapenem-resistance, and aminoglycoside resistant strains of bacteria. The adverse effects of pazufloxacin, such as drug-induced convulsion and hypotension are less than those of other conventional injectable fluoroquinolones.

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