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ChemicalBook > Product Catalogue >Biochemical Engineering >Amino Acids and Derivatives >Other Amino Acid Protection >Benzyl chloroformate

Benzyl chloroformate

Benzyl chloroformate Structure
  • ₹2000 - ₹32610
  • Product name: Benzyl chloroformate
  • CAS: 501-53-1
  • MF: C8H7ClO2
  • MW: 170.59
  • EINECS:207-925-0
  • MDL Number:MFCD00000640
  • Synonyms:CARBONOCHLORIDE ACID BENZYL ESTER;Benzyl chloroformate (CBZ-Cl);Benzyl chloroformate, 95%, stab. with ca 0.1% sodium carbonate;Benzyl Chloroformate (30-35% in Toluene);Carbobenzoxy chloride, Z-chloride;Benzyl chloroformate, 97 WT%, stabilized;Benzyl chloroformate, stabilized;Chloridocarbonic acid benzyl ester
3 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 25G
  • 250ML
  • 250G
  • ManufacturerTCI Chemicals (India)
  • Product numberB3021
  • Product descriptionBenzyl Chloroformate min. 94.0 %
  • Packaging25G
  • Price₹2000
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberB3021
  • Product descriptionBenzyl Chloroformate min. 94.0 %
  • Packaging250G
  • Price₹5000
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number8.14688
  • Product descriptionBenzyl chloroformate (stabilised) for synthesis
  • Packaging250ML
  • Price₹32610
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) B3021 Benzyl Chloroformate min. 94.0 % 25G ₹2000 2022-05-26 Buy
TCI Chemicals (India) B3021 Benzyl Chloroformate min. 94.0 % 250G ₹5000 2022-05-26 Buy
Sigma-Aldrich(India) 8.14688 Benzyl chloroformate (stabilised) for synthesis 250ML ₹32610 2022-06-14 Buy

Properties

Melting point :-20 °C
Boiling point :103 °C20 mm Hg(lit.)
Density :1.212 g/mL at 20 °C
vapor density :1 (vs air)
vapor pressure :1.39 psi ( 20 °C)
refractive index :n20/D 1.519(lit.)
Flash point :197 °F
storage temp. :Store at +2°C to +8°C.
solubility :Miscible with ether, acetone and benzene.
form :Solution
color :slightly yellow to slightly pink
Odor :Irritating; sharp, penetrating.
Water Solubility :decomposes
Sensitive :Moisture Sensitive
Merck :14,1801
Exposure limits :ACGIH: TWA 1 ppm
OSHA: TWA 1 ppm(5 mg/m3)
NIOSH: IDLH 10 ppm; Ceiling 1 ppm(5 mg/m3) Stability :Stable. Incompatible with water, oxidizing agents. Combustible.
CAS DataBase Reference :501-53-1(CAS DataBase Reference)
NIST Chemistry Reference :Benzyl chloroformate(501-53-1)
EPA Substance Registry System :Carbonochloridic acid, phenylmethyl ester (501-53-1)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger GHS hazard pictograms P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H350 May cause cancer Carcinogenicity Category 1A, 1B Danger GHS hazard pictograms
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P201 Obtain special instructions before use.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310 Immediately call a POISON CENTER or doctor/physician.

Description

Benzyl chloroformate is widely used as a reactive chemical intermediate in plastic, pharmaceutical, agricultural and organic chemicals. It is useful for the introduction of carboxybenzyl (cbz) protecting group for amines such as aniline in organic synthesis. It is also involved in the synthesis of 1,2,4-oxadiazoles.

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