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CDN 1163

CDN 1163 Structure
  • ₹10954.9 - ₹44057.75
  • Product name: CDN 1163
  • CAS: 892711-75-0
  • MF: C20H20N2O2
  • MW: 320.39
  • EINECS:
  • MDL Number:MFCD07177494
  • Synonyms:4-isopropoxy-N-(2-methylquinolin-8-yl)benzamide;CDN1163;N-(2-methylquinolin-8-yl)-4-propan-2-yloxybenzamide;4-(1-Methylethoxy)-N-(2-methyl-8-quinolinyl)benzamide;Benzamide, 4-(1-methylethoxy)-N-(2-methyl-8-quinolinyl)-;Inhibitor,CDN 1163,Calcium Channel,Ca channels,Ca2+ channels,CDN-1163,CDN1163,inhibit
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1682
  • Product descriptionCDN1163 ≥98% (HPLC)
  • Packaging5MG
  • Price₹10954.9
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1682
  • Product descriptionCDN1163 ≥98% (HPLC)
  • Packaging25MG
  • Price₹44057.75
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML1682 CDN1163 ≥98% (HPLC) 5MG ₹10954.9 2022-06-14 Buy
Sigma-Aldrich(India) SML1682 CDN1163 ≥98% (HPLC) 25MG ₹44057.75 2022-06-14 Buy

Properties

Melting point :87 - 89°C
storage temp. :2-8°C
solubility :Soluble in DMSO (>25 mg/ml)
form :powder
color :white to beige
Stability :Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

CDN1163 (892711-75-0) is an allosteric activator of the sarco/endoplasmic reticulum Ca2+-ATPase (SERCA).1,2? It lowered fasting glucose levels, improved glucose tolerance, and ameliorated hepatitis steatosis in ob/ob mice.1?? CDN1163 also rescued neurons from ER-stress-induced cell death in vitro and displayed significant efficacy in a rat 6-hydroxydopamine (6-OHDA) model of Parkinson’s disease.2 It reduced age-related muscle atrophy and weakness in a C57BL/6J mice.3? CDN1163 decreased inflammatory cytokines and chemokines and attenuated mitochondrial dysfunction in Influenza A infected H1395 cells.4

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