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ChemicalBook > Product Catalogue >Organic Chemistry >Alcohols,Phenols,Phenol alcohols >CONDURITOL B EPOXIDE

CONDURITOL B EPOXIDE

CONDURITOL B EPOXIDE Structure
  • ₹14797.78 - ₹52771.88
  • Product name: CONDURITOL B EPOXIDE
  • CAS: 6090-95-5
  • MF: C6H10O5
  • MW: 162.14
  • EINECS:
  • MDL Number:MFCD00077326
  • Synonyms:Conduritol B Epoxide - CAS 6090-95-5 - Calbiochem;CONDURITOL C EPOXIDE;conduritolepoxide ;CBE;(+/-) CONDURITOL B EPOXIDE;CONDURITOL B EPOXIDE;DL-1,2-ANHYDRO-MYO-INOSITOL;1,2-Anhydro-myo-inositol
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Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • 100MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberC5424
  • Product descriptionConduritol B epoxide
  • Packaging25MG
  • Price₹52771.88
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number234599
  • Product descriptionConduritol B Epoxide - CAS 6090-95-5 - Calbiochem Conduritol B Epoxide, CAS 6090-95-5, is an irreversible Inhibitor of glucocerebrosidase in neurons. Also inhibits α-glucosidase activity in a variety
  • Packaging100MG
  • Price₹33440
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC5424
  • Product descriptionConduritol B epoxide
  • Packaging5MG
  • Price₹14797.78
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) C5424 Conduritol B epoxide 25MG ₹52771.88 2022-06-14 Buy
Sigma-Aldrich(India) 234599 Conduritol B Epoxide - CAS 6090-95-5 - Calbiochem Conduritol B Epoxide, CAS 6090-95-5, is an irreversible Inhibitor of glucocerebrosidase in neurons. Also inhibits α-glucosidase activity in a variety 100MG ₹33440 2022-06-14 Buy
Sigma-Aldrich(India) C5424 Conduritol B epoxide 5MG ₹14797.78 2022-06-14 Buy

Properties

Melting point :157-159
Boiling point :360.5±42.0 °C(Predicted)
Density :1.925±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. :2-8°C
solubility :Soluble in Water (up to 25 mg/ml) or in DMSO
pka :13.08±0.70(Predicted)
form :White solid
color :White
Stability :Moisture Sensitive

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Conduritol B epoxide (CBE) is an irreversible inhibitor of glucocerebrosidase, also known as acid β-glucosidase, glucosylceramidase, GBA, or GBA1 (IC50 = 9 μM). Inhibition of this lysosomal glucosidase results in the accumulation of glucocerebroside without affecting cell viability, lysosomal enzyme release, or the activity of intracellular enzymes. It also does not inhibit non-lysosomal glucosylceramidase or cytosolic β-glucosidase. As glucocerebrosidase deficiency results in Gaucher disease, a common lysosomal storage disorder that can involve defects in blood, bone, neurological, and liver development, CBE is used in in vitro and animal models of the disease.

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