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ChemicalBook > Product Catalogue >Natural Products >Coumarin >COUMESTROL

COUMESTROL

COUMESTROL Structure
  • ₹4557.33 - ₹19950.48
  • Product name: COUMESTROL
  • CAS: 479-13-0
  • MF: C15H8O5
  • MW: 268.22
  • EINECS:207-525-6
  • MDL Number:MFCD00016885
  • Synonyms:cumoesterol ;COUMOESTROL;7 12-DIHYDROXYCOUMESTAN 98%;Coumesterol;COUMESTROL(P);2-(2 4-DIHYDROXYPHENYL)-6-HYDROXY-3-BENZOFURANCARBOXYLIC ACID D-LACTONE 98%;Coumestrol,99%;3-Benzofurancarboxylic acid, 2-(2,4-dihydroxyphenyl)-6-hydroxy-, .delta.-lactone
Price3 Properties Safety Information Description
3 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 1MG
  • 5MG
  • 50MG
  • ManufacturerSigma-Aldrich(India)
  • Product number27883
  • Product descriptionCoumestrol BioReagent, suitable for fluorescence, ≥97.5% (HPLC)
  • Packaging1MG
  • Price₹4557.33
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number27883
  • Product descriptionCoumestrol BioReagent, suitable for fluorescence, ≥97.5% (HPLC)
  • Packaging5MG
  • Price₹17872.08
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number27885
  • Product descriptionCoumestrol ≥95.0% (HPLC)
  • Packaging50MG
  • Price₹19950.48
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 27883 Coumestrol BioReagent, suitable for fluorescence, ≥97.5% (HPLC) 1MG ₹4557.33 2022-06-14 Buy
Sigma-Aldrich(India) 27883 Coumestrol BioReagent, suitable for fluorescence, ≥97.5% (HPLC) 5MG ₹17872.08 2022-06-14 Buy
Sigma-Aldrich(India) 27885 Coumestrol ≥95.0% (HPLC) 50MG ₹19950.48 2022-06-14 Buy

Properties

Melting point :≥350 °C(lit.)
Boiling point :331.39°C (rough estimate)
Density :1.2586 (rough estimate)
refractive index :1.7680 (estimate)
storage temp. :Refrigerator
solubility :DMSO: soluble
form :Light beige solid.
pka :8.25±0.20(Predicted)
color :Pale Yellow to Dark Brown
BRN :266702
LogP :2.940 (est)
CAS DataBase Reference :479-13-0(CAS DataBase Reference)
EPA Substance Registry System :Coumestrol (479-13-0)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Coumestrol is a phytoestrogen that occurs naturally in soybeans, spinach, and clover. It competitively (vs. 17β-estradiol, ) binds the estrogen receptors ERα (IC50 = 11 nM) and ERβ (IC50 = 2 nM) and can induce ER-dependent gene expression in isolated cells. Coumestrol is also a weak antagonist of pregnane X receptor (IC50 = 12 μM) as well as a potential inverse agonist of the constitutive androstane receptor (EC50 = 30 μM).

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career henan chemical co
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Shaanxi Dideu Medichem Co. Ltd
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₹0.00 /1g
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Biosyn Research Chemicals chakrachem Lifesciences Neugen Labs CHEMAZON LABORATORIES Biosyn Research Chemicals A. B. Enterprises
Chongqing Chemdad Co., Ltd
Neostar United (Changzhou) Industrial Co., Ltd.