CUCURBITACIN B
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- ₹7100 - ₹103292.15
- Product name: CUCURBITACIN B
- CAS: 6199-67-3
- MF: C32H46O8
- MW: 558.7
- EINECS:
- MDL Number:MFCD07778083
- Synonyms:(2beta,9beta,10alpha,16alpha,23e)-thyl ;19-nor-9-beta,10-alpha-lanosta-5,23-diene-3,11,22-trione,2-beta,16-alpha,20,25 ;19-nor-9beta,10alpha-lanosta-5,23-diene-3,11,22-trione,2beta,16alpha,20,25-tet ;19-norlanosta-5,23-diene-3,11,22-trione,25-(acetyloxy)-2,16,20-trihydroxy-9-me ;25-(acetyloxy)-2,16,20-trihydroxy-9-methyl-19-norlanosta-5,23-diene-3,11,22-tr ;Cucurbitacin B hydrate;cucurbitacineb ;AMARINE
4 prices
Selected condition:
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerTCI Chemicals (India)
- Product numberC3442
- Product descriptionCucurbitacin B
- Packaging5MG
- Price₹7100
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberC3442
- Product descriptionCucurbitacin B
- Packaging25MG
- Price₹17800
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberC8499
- Product descriptionCucurbitacin B hydrate ≥97% (HPLC)
- Packaging5MG
- Price₹26542.9
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberC8499
- Product descriptionCucurbitacin B hydrate ≥97% (HPLC)
- Packaging25MG
- Price₹103292.15
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | C3442 | Cucurbitacin B | 5MG | ₹7100 | 2022-05-26 | Buy |
TCI Chemicals (India) | C3442 | Cucurbitacin B | 25MG | ₹17800 | 2022-05-26 | Buy |
Sigma-Aldrich(India) | C8499 | Cucurbitacin B hydrate ≥97% (HPLC) | 5MG | ₹26542.9 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | C8499 | Cucurbitacin B hydrate ≥97% (HPLC) | 25MG | ₹103292.15 | 2022-06-14 | Buy |
Properties
Melting point :184-186°
alpha :D25 +88° (c = 1.55 in ethanol)
Boiling point :546.74°C (rough estimate)
Density :1.0953 (rough estimate)
refractive index :1.4900 (estimate)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMSO: soluble10mg/mL, clear
form :powder
pka :12.60±0.29(Predicted)
color :white to beige
λmax :290nm(EtOH)(lit.)
Merck :14,2614
Stability :Hygroscopic
InChIKey :IXQKXEUSCPEQRD-ALLWXVAWSA-N
alpha :D25 +88° (c = 1.55 in ethanol)
Boiling point :546.74°C (rough estimate)
Density :1.0953 (rough estimate)
refractive index :1.4900 (estimate)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMSO: soluble10mg/mL, clear
form :powder
pka :12.60±0.29(Predicted)
color :white to beige
λmax :290nm(EtOH)(lit.)
Merck :14,2614
Stability :Hygroscopic
InChIKey :IXQKXEUSCPEQRD-ALLWXVAWSA-N
Safety Information
Symbol(GHS): |
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Signal word: | Danger | ||||||||||||||
Hazard statements: |
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Precautionary statements: |
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Description
Cucurbitacin B is a plant-derived triterpene that has the classic four-ring structure of mammalian steroids. It has diverse effects on mammalian cells, most notably inducing cell cycle arrest or apoptosis in a range of cancer cell lines. Cucurbitacin B inhibits the growth of several breast cancer cell lines (IC50s = 18-50 nM). It suppresses the growth of tumors developed from MDA-MB-231 and 4T-1 breast cancer cells in mice. Cucurbitacin B blocks the inflammatory response of macrophages treated with lipopolysaccharide. In Drosophila, it serves as an ecdysteroid receptor antagonist (Kd = 5 μM).Related product price
- Cucurbitacin E
₹24745.95-99395.15 - 4-tert-Butylcyclohexanone
₹1948.5-44000 - CUCURBITACIN B
₹7100-103292.15
Suppliers and manufacturers
TCI Chemicals (India) Pvt. Ltd.
CLEARSYNTH LABS LTD.
Chengdu Biopurify Phytochemicals Ltd.
Shaanxi Pioneer Biotech Co., Ltd .
Neostar United (Changzhou) Industrial Co., Ltd.
SIMAGCHEM CORP