CYNARIN
- ₹54309.03
- Product name: CYNARIN
- CAS: 19870-46-3
- MF: C25H24O12
- MW: 516.45
- EINECS:214-655-7
- MDL Number:MFCD13196505
- Synonyms:1,3-Dicaffeoylquinic acid;(1S,3R,4R,5R)-1,3-Bis[3-(3,4-dihydroxyphenyl)acryloyloxy]-4,5-dihydroxycyclohexanecarboxylic acid;Dicaffeoylquinic Acid, 1,5-;(1S,3R,4R,5R)-1,3-bis[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy]-4,5-dihydroxycyclohexane-1-carboxylic acid;1,5-di-O-Caffeoylquinic acid;Cyclohexanecarboxylic acid, 1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxy-, (1S,3R,4R,5R)-;(1S,3R,4R,5R)-1,3-bis[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy]-4,5-dihydroxycyclohexane-1-carboxylicaci;19870-46-3 CYNARIN
1 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- ManufacturerSigma-Aldrich(India)
- Product number16917
- Product description1,5-Dicaffeoylquinic acid analytical standard
- Packaging5MG
- Price₹54309.03
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 16917 | 1,5-Dicaffeoylquinic acid analytical standard | 5MG | ₹54309.03 | 2022-06-14 | Buy |
Properties
Boiling point :819.9±65.0 °C(Predicted)
Density :1?+-.0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :soluble5mg/mL, clear, colorless to light yellow
form :Solid
pka :2.50±0.50(Predicted)
color :white to off-white
Stability :Hygroscopic
Density :1?+-.0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :soluble5mg/mL, clear, colorless to light yellow
form :Solid
pka :2.50±0.50(Predicted)
color :white to off-white
Stability :Hygroscopic
Safety Information
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Description
1,5-Dicaffeoylquinic acid (1,5-DCQA) has been found in A. montana and is an HIV-1 integrase inhibitor and free radical scavenger. 1,5-DCQA inhibits HIV-1 integrase 3'' end processing, end joining, and disintegration with IC50 values of 0.35, 0.56, and 0.84 μg/ml, respectively. It also inhibits HIV-1 replication in MT-2 T lymphoblastoid cells with an ED50value of 2 μg/ml. 1,5-DCQA (0.25-1 μM) reduces the level of free radicals released from human polymorphonuclear (PMN) cells stimulated by N-formyl-Met-Leu-Phe (fMLP; ) in a dose-dependent manner. It also dose-dependently increases cell survival and glutathione (GSH) levels and decreases reactive oxygen species (ROS) production and lactate dehydrogenase (LDH) release in an oxygen-glucose deprivation/reperfusion assay in rat cerebral astrocytes when used at concentrations ranging from 5 to 100 μM.More related product prices
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