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ChemicalBook > Product Catalogue >Biochemical Engineering >Plant extracts >Cynarin

Cynarin

Cynarin Structure
  • ₹37194.7
  • Product name: Cynarin
  • CAS: 30964-13-7
  • MF: C25H24O12
  • MW: 516.45
  • EINECS:214-655-7
  • MDL Number:MFCD00867168
  • Synonyms:1,5-DICAFFEOYLQUINIC ACID;1,3-DICAFFEOYLQUINIC ACID;Dicaffeoylquinic Acid, 1,3-;(1R,3R,4S,5R)-1,3-Bis((3-(3,4-dihydroxyphenyl)acryloyl)oxy)-4,5-dihydroxycyclohexanecarboxylic acid;CYNARIN(ECHINACEA);CYNARIN(ARTICHOKE);CYNARIN;CINARINE
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Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • ManufacturerSigma-Aldrich(India)
  • Product number91801
  • Product descriptionCynarin analytical standard
  • Packaging5MG
  • Price₹37194.7
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 91801 Cynarin analytical standard 5MG ₹37194.7 2022-06-14 Buy

Properties

Melting point :225-227°
alpha :D25 -59° (c = 2 in methanol)
Boiling point :819.9±65.0 °C(Predicted)
Density :1?+-.0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :methanol: soluble5mg/mL, clear, light yellow to yellow
pka :2.58±0.50(Predicted)
form :Solid
color :faint yellow to yellow
Stability :Hygroscopic
LogP :1.640 (est)
CAS DataBase Reference :30964-13-7(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

1,3-Dicaffeoylquinic acid is a polyphenol that has been found in C. scolymus. It decreases the expression and protein levels of inducible nitric oxide synthase (iNOS) when used at a concentration of 10 μM in human coronary artery smooth muscle cells (HCASMCs) treated with a cytokine mixture. 1,3-Dicaffeoylquinic acid decreases protein levels of tyrosinase and microphthalmia-associated transcription factor (MITF) in B16F1 murine melanocytes. It inhibits melanogenesis in B16F1 cells and decreases tyrosinase activity in cell lysates when used at a concentration of 25 μM. 1,3-Dicaffeoylquinic acid (20 and 40 μM) reduces triglyceride levels in sodium oleate-induced hyperlipidemic HepG2 cells compared to hyperlipidemic control cells.

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