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ChemicalBook > Product Catalogue >API >Circulatory system drugs >Antiarrhythmics Drugs >Celiprolol hydrochloride

Celiprolol hydrochloride

Celiprolol hydrochloride Structure
  • ₹14685
  • Product name: Celiprolol hydrochloride
  • CAS: 57470-78-7
  • MF: C20H34ClN3O4
  • MW: 415.95
  • EINECS:260-752-2
  • MDL Number:MFCD00941500
  • Synonyms:ffhcl ;rhc-5320a ;selectrol ;st1396clorhidrato ;st1396hydrochlorid ;st1396hydrochloride ;3-(3-acetyl-4-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)phenyl)-1,1-ure ;3-(3-acetyl-4-(3-tert-butylamino-2-hydroxypropoxy)phenyl)-1,1-diethylharnsto
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Selected condition:

Brand

  • ALFA India

Package

  • 10mg
  • ManufacturerALFA India
  • Product numberALF-J65943-MA
  • Product descriptionCeliprolol hydrochloride
  • Packaging10mg
  • Price₹14685
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ALFA India ALF-J65943-MA Celiprolol hydrochloride 10mg ₹14685 2022-05-26 Buy

Properties

Melting point :197-200°C (dec.)
RTECS :YR6560000
storage temp. :Refrigerator
solubility :Freely soluble in water and in methanol, soluble in ethanol (96 per cent), very slightly soluble in methylene chloride.
form :Solid
color :White to Off-White
Water Solubility :Soluble in ethanol, methanol and water
CAS DataBase Reference :57470-78-7(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H303 May be harmfulif swallowed Acute toxicity,oral Category 5 P312
Precautionary statements:
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P403 Store in a well-ventilated place.

Description

Celiprolol is a β1 adrenergic receptor antagonist and a β2 adrenergic receptor partial agonist that has been shown to relax human arteries and veins with ED50 values of 40-50 μM in vitro. At 1-10 mg/kg/h, celiprolol can reduce myocardial infarct size and increase nitric oxide (NO) production in a rabbit model of myocardial ischemia. Furthermore, 100 mg/kg/d celiprolol has been reported to stimulate expression and activate phosphorylation of endothelial NO synthase in rat cardiac myocytes.

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