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ChemicalBook > Product Catalogue >API >Antibiotics >Cephalosporins Drugs >Cephalexin

Cephalexin

Cephalexin Structure
  • ₹2220 - ₹19380
  • Product name: Cephalexin
  • CAS: 15686-71-2
  • MF: C16H17N3O4S
  • MW: 347.39
  • EINECS:239-773-6
  • MDL Number:MFCD04966776
  • Synonyms:(6r-(6alpha,7beta(r*)))-ino)-3-methyl-8-oxo ;5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylicacid,7-((aminophenylacetyl)am ;5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylicacid,7-(2-amino-2-phenylaceta ;7-(d-2-amino-2-phenylacetamido)-3-methyl-delta(sup3)-cephem-4-carboxylica ;7-(d-2-amino-2-phenylacetamido)-3-methyl-delta3-cephem-4-carboxylicacid ;7-(d-alpha-aminophenylacetamido)desacetoxycephalosporanicacid ;7-beta-(d-alpha-amino-alpha-phenylacetylamino)-3-methyl-3-cephem-4-carboxyli ;cefa-iskia
5 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)
  • SRL

Package

  • 100MG
  • 1G
  • 1Gms
  • 5Gms
  • 25Gms
  • ManufacturerSigma-Aldrich(India)
  • Product number33989
  • Product descriptionCefalexin VETRANAL?, analytical standard
  • Packaging100MG
  • Price₹11236.35
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1848
  • Product descriptionCephalexin Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹15144.18
  • Updated2022-06-14
  • Buy
  • ManufacturerSRL
  • Product number56338
  • Product descriptionCephalexin Hydrate (CFL), 95-103%
  • Packaging1Gms
  • Price₹2220
  • Updated2022-05-26
  • Buy
  • ManufacturerSRL
  • Product number56338
  • Product descriptionCephalexin Hydrate (CFL), 95-103%
  • Packaging5Gms
  • Price₹8240
  • Updated2022-05-26
  • Buy
  • ManufacturerSRL
  • Product number56338
  • Product descriptionCephalexin Hydrate (CFL), 95-103%
  • Packaging25Gms
  • Price₹19380
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 33989 Cefalexin VETRANAL?, analytical standard 100MG ₹11236.35 2022-06-14 Buy
Sigma-Aldrich(India) PHR1848 Cephalexin Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹15144.18 2022-06-14 Buy
SRL 56338 Cephalexin Hydrate (CFL), 95-103% 1Gms ₹2220 2022-05-26 Buy
SRL 56338 Cephalexin Hydrate (CFL), 95-103% 5Gms ₹8240 2022-05-26 Buy
SRL 56338 Cephalexin Hydrate (CFL), 95-103% 25Gms ₹19380 2022-05-26 Buy

Properties

Melting point :196-198°C
alpha :[α]D20 +144~+158° (c=0.5, H2O) (Calculated on dehydrous basis)
Boiling point :727.4±60.0 °C(Predicted)
Density :1.3040 (rough estimate)
refractive index :1.6320 (estimate)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :NH4OH 1 M: 50 mg/mL, clear, yellow
form :Solid
pka :5.2, 7.3(at 25℃)
color :White to light yellow
PH :pH (5g/l, 25℃) 3.5~5.5
Water Solubility :12.5g/L(25 ºC)
Merck :13,1986
BCS Class :4
InChIKey :AVGYWQBCYZHHPN-CYJZLJNKSA-N
CAS DataBase Reference :15686-71-2(CAS DataBase Reference)
EPA Substance Registry System :5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-methyl-8-oxo-, (6R,7R)- (15686-71-2)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger GHS hazard pictograms P261, P285, P304+P341, P342+P311,P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P284 Wear respiratory protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P333+P313 IF SKIN irritation or rash occurs: Get medical advice/attention.

Description

Cephalexin is a cephalosporin antibiotic used to study the effect of expression, binding, and inhibition of PBP3 and other penicillin-binding proteins (PBPs) on bacterial cell wall mucopeptide synthesis. Cephalexin disrupts the synthesis of the peptidoglycan layer of bacterial cell walls which is responsible for cell wall structural integrity. Peptidoglycan synthesis is facilitated by transpeptidases known as penicillin-binding proteins (PBPs). PBPs bind to the D-Ala-D-Ala at the end of muropeptides (peptidoglycan precursors) to crosslink the peptidoglycan. Cephalexin antibiotics mimic the D-Ala-D-Ala site, thereby competitively inhibiting PBP crosslinking of peptidoglycan.

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