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ChemicalBook > Product Catalogue >API >Anesthetic Agents >Skeletal muscle relaxants >Chlorzoxazone

Chlorzoxazone

Chlorzoxazone Structure
  • ₹2400 - ₹24377.9
  • Product name: Chlorzoxazone
  • CAS: 95-25-0
  • MF: C7H4ClNO2
  • MW: 169.57
  • EINECS:202-403-9
  • MDL Number:MFCD00005717
  • Synonyms:Biomioran;component of Parafon Forte;Escoflex;Miotran;Myoflexin;Myoflexine;Neoflex;parafonforte
Price4 Properties Safety Information Description
4 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 500MG
  • 25G
  • 100G
  • ManufacturerTCI Chemicals (India)
  • Product numberC2237
  • Product descriptionChlorzoxazone min. 98.0 %
  • Packaging25G
  • Price₹2400
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1919
  • Product descriptionChlorzoxazone Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging500MG
  • Price₹19863.88
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC4397
  • Product descriptionChlorzoxazone
  • Packaging100G
  • Price₹24377.9
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC4397
  • Product descriptionChlorzoxazone
  • Packaging25G
  • Price₹8898.15
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) C2237 Chlorzoxazone min. 98.0 % 25G ₹2400 2022-05-26 Buy
Sigma-Aldrich(India) PHR1919 Chlorzoxazone Pharmaceutical Secondary Standard; Certified Reference Material 500MG ₹19863.88 2022-06-14 Buy
Sigma-Aldrich(India) C4397 Chlorzoxazone 100G ₹24377.9 2022-06-14 Buy
Sigma-Aldrich(India) C4397 Chlorzoxazone 25G ₹8898.15 2022-06-14 Buy

Properties

Melting point :191-192 °C (lit.)
Density :1.3771 (rough estimate)
refractive index :1.5557 (estimate)
storage temp. :room temp
solubility :DMSO: soluble50mg/mL, clear
pka :pKa 8.3 (Uncertain)
form :Powder
color :white to off-white
Water Solubility :0.1 g/100 mL
Merck :14,2194
LogP :1.816 (est)
CAS DataBase Reference :95-25-0(CAS DataBase Reference)
NIST Chemistry Reference :Chlorzoxazone(95-25-0)
EPA Substance Registry System :Chlorzoxazone (95-25-0)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Chlorzoxazone is a benzoxazolone derivative that causes skeletal muscle relaxation and blocks spasticity in clinical studies. Chlorzoxazone enhances small and intermediate conductance calcium-activated potassium channels (EC50s = 87 and 98 μM for KCa2.2 and KCa3.1, respectively). The cytochrome P450 isoform CYP2E1 converts chlorzoxazone to 6-hydroxy chlorzoxazone . The urinary excretion of this 6-hydroxy metabolite is often used as a probe of CYP2E1 activity in studies of hepatotoxicity.

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