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ChemicalBook > Product Catalogue >API >Circulatory system drugs >Calcium channel blockers >Cilnidipine

Cilnidipine

Cilnidipine Structure
  • ₹7900 - ₹70135.18
  • Product name: Cilnidipine
  • CAS: 132203-70-4
  • MF: C27H28N2O7
  • MW: 492.52
  • EINECS:634-350-6
  • MDL Number:MFCD00865853
  • Synonyms:(+/-)-(e)-cinnamyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate;O3-(2-Methoxyethyl) O5-[(E)-3-phenylprop-2-enyl] 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylic acid 3-(2-methoxyethyl)5-[(E)-3-phenyl-2-propenyl] ester;2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylic acid 3-(2-methoxyethyl)5-[(E)-3-phenyl-2-propenyl] ester;Frc 8653,1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-methoxyethyl (2E)-3-phenyl-2-propenyl ester;1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 2-Methoxyethyl (2E)-3-Phenyl-2-propenyl Ester 2-Methoxyethyl (2E)-3-Phenyl-2-propenyl 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate;ilnidipine;3-CinnaMyl 5-(2-Methoxyethyl) 2,6-diMethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
4 prices
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • 1G
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberC2564
  • Product descriptionCilnidipine
  • Packaging1G
  • Price₹7900
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberC2564
  • Product descriptionCilnidipine
  • Packaging5G
  • Price₹9800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC1493
  • Product descriptionCilnidipine ≥98% (HPLC), powder
  • Packaging10MG
  • Price₹16367.4
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC1493
  • Product descriptionCilnidipine ≥98% (HPLC), powder
  • Packaging50MG
  • Price₹70135.18
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) C2564 Cilnidipine 1G ₹7900 2022-05-26 Buy
TCI Chemicals (India) C2564 Cilnidipine 5G ₹9800 2022-05-26 Buy
Sigma-Aldrich(India) C1493 Cilnidipine ≥98% (HPLC), powder 10MG ₹16367.4 2022-06-14 Buy
Sigma-Aldrich(India) C1493 Cilnidipine ≥98% (HPLC), powder 50MG ₹70135.18 2022-06-14 Buy

Properties

Melting point :97-99°C
Boiling point :652.6±55.0 °C(Predicted)
Density :1.240±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :H2O: ≤2mg/mL
pka :2.61±0.70(Predicted)
form :powder
color :light yellow
Merck :14,2275
InChIKey :KJEBULYHNRNJTE-DHZHZOJOSA-N
CAS DataBase Reference :132203-70-4(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Clinidipine is a kind of calcium channel blocker. It is a kind of novel calcium antagonist with the blocking effect on both L-type and N-type calcium channels. It is mainly used for the treatment of hypertension. Based on its effect on both N-type and L-type calcium channel, it can dilate both arterioles and venules, further reducing the pressure in the capillary bed. In addition, cilinidipine can attenuate the platelet activation associated with catecholamines.

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