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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Metabolism >PDE inhibitors >Cilomilast

Cilomilast

Cilomilast Structure
  • ₹17157.63 - ₹69648.05
  • Product name: Cilomilast
  • CAS: 153259-65-5
  • MF: C20H25NO4
  • MW: 343.42
  • EINECS:200-258-5
  • MDL Number:MFCD00924373
  • Synonyms:4-cyano-4-(3-cyclopentyloxy-4-methoxy-phenyl)cyclohexane-1-carboxylic acid;Cilomilast, SB 207499, Ariflo;"(cilomilast) 4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphenyl)cyclohexane-1-carboxylic acid";CILOMILAST;Clomilast;Cilomelast;Ariflo;cis-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-4-cyanocyclohexane-1-carboxylic Acid
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0733
  • Product descriptionCilomilast ≥95% (HPLC)
  • Packaging5MG
  • Price₹17157.63
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0733
  • Product descriptionCilomilast ≥95% (HPLC)
  • Packaging25MG
  • Price₹69648.05
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML0733 Cilomilast ≥95% (HPLC) 5MG ₹17157.63 2022-06-14 Buy
Sigma-Aldrich(India) SML0733 Cilomilast ≥95% (HPLC) 25MG ₹69648.05 2022-06-14 Buy

Properties

Melting point :157°C
Boiling point :549.1±50.0 °C(Predicted)
Density :1.21±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble15mg/mL, clear
form :powder
pka :4.45±0.25(Predicted)
color :white to beige
InChIKey :CFBUZOUXXHZCFB-OYOVHJISSA-N

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Cilomilast-d9 is a deuterium-labeled compound that is an inhibitor of phosphodiesterase enzymes, particularly LPDE4 and HPDE4, with IC50 = 100 nM and 120 nM, respectively. These phosphodiesterases are responsible for the hydrolysis of cAMP, a secondary messenger molecule with a variety of roles. Prolonging the lifetime of cAMP has a potentiating effect on signal transduction.

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