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ChemicalBook > Product Catalogue >API >Antiallergic drugs >Antihistamines >Clemastine fumarate

Clemastine fumarate

Clemastine fumarate Structure
  • ₹9482.7
  • Product name: Clemastine fumarate
  • CAS: 14976-57-9
  • MF: C25H30ClNO5
  • MW: 459.96
  • EINECS:239-055-2
  • MDL Number:MFCD00137486
  • Synonyms:CLEMASTINE FUMARATE;CLEMASTINE FUMARATE SALT;(+)-2-(2-((p-chloro-alpha-methyl-alpha-phenylbenzyl)oxy)ethyl)-1-methylpyrro ;(+)-2-(2-((p-chloro-alpha-methyl-alpha-phenylbenzyl)oxy)ethyl)-1-methylpyrroli ;(+)-lfumarate(1:1) ;1-methyl-2-(2-(methyl-p-chlorodiphenylmethyloxy)ethyl)pyrrolidine ;(2R)-2-[2-[(1R)-1-(4-CHLOROPHENYLETHOXY)]ETHYL]-1-METHYL-2-PYRROLIDINE FUMARATE;2-(2-(1-(4-chlorophenyl)-1-phenylethoxy)ethyl)-1-methylpyrrolidine
Price1 Properties Safety Information Description
1 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 100MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0445
  • Product descriptionClemastine fumarate salt ≥98% (HPLC)
  • Packaging100MG
  • Price₹9482.7
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML0445 Clemastine fumarate salt ≥98% (HPLC) 100MG ₹9482.7 2022-06-14 Buy

Properties

Melting point :158-162°C
alpha :D21 +16.9° (methanol)
Boiling point :154°C (rough estimate)
Density :1.0247 (rough estimate)
refractive index :1.5790 (estimate)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL (clear solution; warmed)
form :powder
color :white to beige
optical activity :[α]/D +15 to +25°, c = 1 in methanol
InChIKey :PMGQWSIVQFOFOQ-YKVZVUFRSA-N
CAS DataBase Reference :14976-57-9(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Clemastine is a selective histamine H1 receptor antagonist (Ki = 0.26 nM) that also displays high affinity for muscarinic receptors (Ki = 16 nM). It has also recently been identified as a positive allosteric modulator of P2X7 receptor signaling. Clemastine has long been used to inhibit histamine-induced bronchoconstriction in asthma and airway hyperresponsive studies.

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Disodium fumarate Dimethyl fumarate Ketotifen fumarate Trinexapac-ethyl DIETHOXYMETHANE Ferrous fumarate 4-Ethoxyphenol 2-Ethoxyethanol Fumaric acid Ethyl acetate Etanol Bisoprolol fumarate Ethoxyquin 2-Ethoxyphenol Ethylparaben Ethyltriphenylphosphonium bromide 123-06-8 Diethyl ether 4-Chlorobenzhydrol

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Suppliers and manufacturers

Hebei Mojin Biotechnology Co., Ltd
Clemastine fumarate
₹0.00 /25KG
Clemastine fumarate CAS:14976-57-9
Henan Bao Enluo International TradeCo.，LTD
Clemastine fumarate
₹100.00 /1kg
Clemastine fumarate CAS:14976-57-9
Hebei Mojin Biotechnology Co.,Ltd
Clemastine fumarate
₹0.00 /25kg
Clemastine fumarate CAS:14976-57-9
SynZeal Research Pvt Ltd Pharmaffiliates Analytics and Synthetics P. Ltd Pharma Affiliates Clearsynth Labs A.J Chemicals CLEARSYNTH LABS LTD.
Capot Chemical Co.,Ltd.