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ChemicalBook > Product Catalogue >API >Hormones and the Endocrine System >Prostaglandin drugs >(-)-Corey lactone diol

(-)-Corey lactone diol

(-)-Corey lactone diol Structure
  • ₹5700 - ₹34878.15
  • Product name: (-)-Corey lactone diol
  • CAS: 32233-40-2
  • MF: C8H12O4
  • MW: 172.18
  • EINECS:608-721-8
  • MDL Number:MFCD00075234
  • Synonyms:(-)-COREY LACTONE DIOL,98%;(3AR,4S,5R,6AS)-(-)-HEXAHYDRO-5-HYDROXY-4--2H-CYCLOPENTA(B)FURAN-2-ONE,;(1R)-2β-(Hydroxymethyl)-3α,5α-dihydroxycyclopentane-1α-acetic acid 1,5-lactone;(1S,5R,6S,7R)-7-Hydroxy-6-hydroxymethyl-2-oxabicyclo[3.3.0]octan-3-one;(3aβ,4S,6aβ)-4β-(Hydroxymethyl)-5α-hydroxyhexahydro-2H-cyclopenta[b]furan-2-one;(-)-6beta-Hydroxymethyl-7alpha-hydroxy-cis-2-oxabicyclo[3.3.0]octan-3-one,98%;(+)-6β-Hydroxymethyl-7α-hydroxy-cis-2-oxabicyclo[3.3.0]octan-3-one;(-)-6-β-Hydroxymethyl-7-α-hydroxy-cis-2-oxabicyclo[3.3.0]octan-3-one ,98%
Price5 Properties Safety Information Description
5 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • ALFA India

Package

  • 200MG
  • 250mg
  • 1G
  • ManufacturerTCI Chemicals (India)
  • Product numberH1418
  • Product description(-)-Corey Lactone Diol min. 98.0 %
  • Packaging200MG
  • Price₹5700
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberH1418
  • Product description(-)-Corey Lactone Diol min. 98.0 %
  • Packaging1G
  • Price₹14200
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number341576
  • Product description(3aR,4S,5R,6aS)-(−)-Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one 98%
  • Packaging1G
  • Price₹34878.15
  • Updated2022-06-14
  • Buy
  • ManufacturerALFA India
  • Product numberALF-H56119-MD
  • Product description(3aR,4S,5R,6aS)-(-)-Hexahydro-5-hydroxy-4-hydroxymethyl-2H-cyclopenta[b]furan-2-one, 98%
  • Packaging250mg
  • Price₹29311
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-H56119-03
  • Product description(3aR,4S,5R,6aS)-(-)-Hexahydro-5-hydroxy-4-hydroxymethyl-2H-cyclopenta[b]furan-2-one, 98%
  • Packaging1g
  • Price₹26100
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) H1418 (-)-Corey Lactone Diol min. 98.0 % 200MG ₹5700 2022-05-26 Buy
TCI Chemicals (India) H1418 (-)-Corey Lactone Diol min. 98.0 % 1G ₹14200 2022-05-26 Buy
Sigma-Aldrich(India) 341576 (3aR,4S,5R,6aS)-(−)-Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one 98% 1G ₹34878.15 2022-06-14 Buy
ALFA India ALF-H56119-MD (3aR,4S,5R,6aS)-(-)-Hexahydro-5-hydroxy-4-hydroxymethyl-2H-cyclopenta[b]furan-2-one, 98% 250mg ₹29311 2022-05-26 Buy
ALFA India ALF-H56119-03 (3aR,4S,5R,6aS)-(-)-Hexahydro-5-hydroxy-4-hydroxymethyl-2H-cyclopenta[b]furan-2-one, 98% 1g ₹26100 2022-05-26 Buy

Properties

Melting point :117-119 °C(lit.)
Boiling point :262.49°C (rough estimate)
Density :1.2104 (rough estimate)
refractive index :1.4455 (estimate)
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO (Slightly), Methanol (Slightly)
pka :14.36±0.40(Predicted)
form :Crystalline Powder or Crystals
color :White to beige-brown
optical activity :[α]20/D 44°, c = 1.4 in methanol
InChIKey :VYTZWRCSPHQSFX-GBNDHIKLSA-N
CAS DataBase Reference :32233-40-2(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Corey aldehyde is a versatile, hydroxy-lactone intermediate for the synthesis of prostaglandins and prostaglandin analogs. Prostaglandin derivatives with modifications in the α chain, the ω chain, or both, are readily accessible from this general intermediate. (?)-Corey lactone diol is simply the reduced version of Corey aldehyde, with alcohol groups at both C-11 and C-13. This allows the introduction of ω chain constituents via alternate chemistries, such as nucleophilic displacements.

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