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ChemicalBook > Product Catalogue >Chemical Reagents >Organic reagents >Thiol ester >Cystamine dihydrochloride

Cystamine dihydrochloride

Cystamine dihydrochloride Structure
  • ₹2294.9 - ₹61962.3
  • Product name: Cystamine dihydrochloride
  • CAS: 56-17-7
  • MF: C4H14Cl2N2S2
  • MW: 225.2
  • EINECS:200-260-7
  • MDL Number:MFCD00012905
  • Synonyms:2,2’-dithiobis-ethanamindihydrochloride ;2,2’-dithiobis-ethylamindihydrochloride ;2-aminoethyldisulfidedihydrochloride ;Cystamine dihydrochloride, 98+%;bis-B-aminoethyldisulphide dihydrochloride;2,2μ-Diaminodiethyl disulfide dihydrochloride, 2,2μ-Dithiobis(ethylamine) dihydrochloride, Decarboxycystine dihydrochloride;Ethylamine, 2,2'-dithiobis-, dihydrochloride;Cystamine dihydrochloride,2,2′-Diaminodiethyl disulfide dihydrochloride, 2,2′-Dithiobis(ethylamine) dihydrochloride, Decarboxycystine dihydrochloride
15 prices
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Brand

  • Sigma-Aldrich
  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • ottokemi

Package

  • 25gm
  • 25G
  • 100gm
  • 100G
  • 500gm
  • 500G
  • ManufacturerSigma-Aldrich
  • Product number30050
  • Product descriptionCystamine dihydrochloride purum, ≥98.0% (AT)
  • Packaging25G
  • Price₹5888.8
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number30050
  • Product descriptionCystamine dihydrochloride purum, ≥98.0% (AT)
  • Packaging100G
  • Price₹11896.68
  • Updated2022-06-14
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberC0875
  • Product descriptionCystamine Dihydrochloride
  • Packaging25G
  • Price₹3300
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberC0875
  • Product descriptionCystamine Dihydrochloride
  • Packaging100G
  • Price₹5800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberC0875
  • Product descriptionCystamine Dihydrochloride
  • Packaging500G
  • Price₹14900
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC121509
  • Product descriptionCystamine dihydrochloride 96%
  • Packaging25G
  • Price₹2294.9
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number30050
  • Product descriptionCystamine dihydrochloride purum, ≥98.0% (AT)
  • Packaging25G
  • Price₹5888.8
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC121509
  • Product descriptionCystamine dihydrochloride 96%
  • Packaging100G
  • Price₹6754.8
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number30050
  • Product descriptionCystamine dihydrochloride purum, ≥98.0% (AT)
  • Packaging100G
  • Price₹11896.68
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC121509
  • Product descriptionCystamine dihydrochloride 96%
  • Packaging500G
  • Price₹22894.88
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC8707
  • Product descriptionCystamine dihydrochloride BioXtra
  • Packaging25G
  • Price₹25557.83
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC8707
  • Product descriptionCystamine dihydrochloride BioXtra
  • Packaging100G
  • Price₹61962.3
  • Updated2022-06-14
  • Buy
  • Manufacturerottokemi
  • Product number C 4501
  • Product descriptionCystamine dihydrochloride 97%
  • Packaging25gm
  • Price₹2979
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number C 4501
  • Product descriptionCystamine dihydrochloride 97%
  • Packaging100gm
  • Price₹5292
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number C 4501
  • Product descriptionCystamine dihydrochloride 97%
  • Packaging500gm
  • Price₹14895
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich 30050 Cystamine dihydrochloride purum, ≥98.0% (AT) 25G ₹5888.8 2022-06-14 Buy
Sigma-Aldrich 30050 Cystamine dihydrochloride purum, ≥98.0% (AT) 100G ₹11896.68 2022-06-14 Buy
TCI Chemicals (India) C0875 Cystamine Dihydrochloride 25G ₹3300 2022-05-26 Buy
TCI Chemicals (India) C0875 Cystamine Dihydrochloride 100G ₹5800 2022-05-26 Buy
TCI Chemicals (India) C0875 Cystamine Dihydrochloride 500G ₹14900 2022-05-26 Buy
Sigma-Aldrich(India) C121509 Cystamine dihydrochloride 96% 25G ₹2294.9 2022-06-14 Buy
Sigma-Aldrich(India) 30050 Cystamine dihydrochloride purum, ≥98.0% (AT) 25G ₹5888.8 2022-06-14 Buy
Sigma-Aldrich(India) C121509 Cystamine dihydrochloride 96% 100G ₹6754.8 2022-06-14 Buy
Sigma-Aldrich(India) 30050 Cystamine dihydrochloride purum, ≥98.0% (AT) 100G ₹11896.68 2022-06-14 Buy
Sigma-Aldrich(India) C121509 Cystamine dihydrochloride 96% 500G ₹22894.88 2022-06-14 Buy
Sigma-Aldrich(India) C8707 Cystamine dihydrochloride BioXtra 25G ₹25557.83 2022-06-14 Buy
Sigma-Aldrich(India) C8707 Cystamine dihydrochloride BioXtra 100G ₹61962.3 2022-06-14 Buy
ottokemi C 4501 Cystamine dihydrochloride 97% 25gm ₹2979 2022-05-26 Buy
ottokemi C 4501 Cystamine dihydrochloride 97% 100gm ₹5292 2022-05-26 Buy
ottokemi C 4501 Cystamine dihydrochloride 97% 500gm ₹14895 2022-05-26 Buy

Properties

Melting point :217-220 °C (dec.)(lit.)
storage temp. :Store below +30°C.
solubility :H2O: soluble1.0g/10 mL, clear to almost clear, colorless to almost colorless (<5.5 NTU)
form :Crystalline Powder, Crystals or Chunks
color :White to yellow
Water Solubility :soluble
Sensitive :Hygroscopic
Merck :14,2776
BRN :3616850
Stability :Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference :56-17-7(CAS DataBase Reference)
EPA Substance Registry System :Ethanamine, 2,2'-dithiobis-, dihydrochloride (56-17-7)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501 Dispose of contents/container to..…

Description

Tissue transglutaminase (TGM2) post-translationally modifies proteins by catalyzing intermolecular cross-linkages between glutamine and lysine side chains. TGM2 has roles in neurodegenerative disorders, celiac sprue, cancer, and fibrotic diseases. Cystamine is an organic disulfide that inhibits TGM2 with an IC50 value of approximately 2.5 mM. It is orally available and is neuroprotective in mouse models of Huntington’s disease. Cystamine also inhibits caspase 3, increases intracellular glutathione, and reduces inflammation in a rat model of inflammatory bowel disease.

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