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ChemicalBook > Product Catalogue >Analytical Chemistry >Standard >Food and cosmetics standards >DIACETOXYSCIRPENOL

DIACETOXYSCIRPENOL

DIACETOXYSCIRPENOL Structure
  • ₹41349.7
  • Product name: DIACETOXYSCIRPENOL
  • CAS: 2270-40-8
  • MF: C19H26O7
  • MW: 366.41
  • EINECS:218-873-3
  • MDL Number:MFCD00866334
  • Synonyms:Diacetoxyscirpenol, FroM FusariuM sp.;Spiro(2,5-methano-1-benzoxepin-10,2'-oxirane)-5a(6H)-methanol, 2,3,4,5,7,9a-hexahydro-3,4-dihydroxy-5,8-dimethyl-, 4,5a-diacetate;Trichothec-9-ene, 12,13-epoxy-4-beta,15-diacetoxy-3-alpha-hydroxy-;Trichothec-9-ene, 12,13-epoxy-4beta,15-diazetoxy-3alpha-hydroxy-;Trichothec-9-ene-3,4,15-triol, 12,13-epoxy-, 4,15-diacetate;Trichothec-9-ene-3,4,15-triol, 12,13-epoxy-, 4,15-diacetate, (3alpha,4beta)-;trichothec-9-ene-3,4,15-triol,12,13-epoxy-,4,15-diacetate,(3-alpha,4-beta) ;Trichothec-9-ene-3alpha,4beta,15-triol, 12,13-epoxy-, 4,15-diacetate
Price1 Properties Safety Information Description
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Brand

  • Sigma-Aldrich(India)

Package

  • 1ML
  • ManufacturerSigma-Aldrich(India)
  • Product number34137
  • Product descriptionDiacetoxyscirpenol solution ~100?μg/mL in acetonitrile, analytical standard
  • Packaging1ML
  • Price₹41349.7
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 34137 Diacetoxyscirpenol solution ~100?μg/mL in acetonitrile, analytical standard 1ML ₹41349.7 2022-06-14 Buy

Properties

Melting point :162-164℃
Boiling point :407.62°C (rough estimate)
Density :1.1821 (rough estimate)
refractive index :1.4790 (estimate)
Flash point :2 °C
storage temp. :2-8°C
solubility :DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml; DMSO: 30 mg/ml; Ethanol: 20 mg/ml
form :A crystalline solid
pka :13.40±0.70(Predicted)
color :Crystals from EtOAc

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P262 Do not get in eyes, on skin, or on clothing.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Diacetoxyscirpenol (DAS) is a potent, trichothecene mycotoxin produced by certain Fusarium strains, which play an important role as plant pathogens, causing a wide range of diseases. It is toxic to fungi, plants, animals, and various mammalian cell cultures, inhibiting de novo protein synthesis. In a biological activity assay, DAS was shown to inhibit expression of the Arabidopsis MAMP-responsive reporter gene WRKY29p::GUS with an IC50 value of 50 nM, thereby suppressing a rapid cell death immune response important for plant defense.

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