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ChemicalBook > Product Catalogue >API >Respiratory Drugs >Asthma drugs >Diprophylline

Diprophylline

Diprophylline Structure
  • ₹0
  • Product name: Diprophylline
  • CAS: 479-18-5
  • MF: C10H14N4O4
  • MW: 254.24
  • EINECS:207-526-1
  • MDL Number:MFCD00005759
  • Synonyms:7-(2,3-Dihydroxypropyl)-1,3-dimethylxanthine;1H-Purine-2,6-dione, 7-(2,3-dihydroxypropyl)-3,7-dihydro-1,3-dimethyl-;1h-purine-2,6-dione,7-(2,3-dihydroxypropyl)-3,7-dihydro-1,3-dimethyl ;7-(2,3-Dihydroxypropyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione;circair ;component of Dilor g;component of Neothylline-gg;Coronal
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :161-162 °C(lit.)
Boiling point :397.46°C (rough estimate)
Density :1.3036 (rough estimate)
refractive index :1.6200 (estimate)
storage temp. :Keep in dark place,Inert atmosphere,Room temperature
solubility :Freely soluble in water, slightly soluble in ethanol (96 per cent).
form :Powder
pka :13.74±0.20(Predicted)
color :White
Water Solubility :33 g/100 mL (25 ºC)
Merck :14,3479
BRN :284563
Stability :Hygroscopic
LogP :-1.100 (est)
CAS DataBase Reference :479-18-5(CAS DataBase Reference)
NIST Chemistry Reference :Dyphylline(479-18-5)
EPA Substance Registry System :Dyphylline (479-18-5)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:

Description

Dyphylline is a xanthine derivative that acts as an A1 and A2 adenosine receptor antagonist and phosphodiesterase inhibitor and exhibits bronchodilator and vasodilator effects. It also moderately inhibits microsomal prostaglandin E synthase-1 with an IC50 value of 200 μM and downregulates ABCG2 drug transporter expression in multidrug resistant tumor cells.

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Suppliers and manufacturers

Bakul Pharma Private Limited HRV Global Life Sciences CLEARSYNTH LABS LTD. A.J Chemicals Pharmaffiliates Analytics and Synthetics P. Ltd Swapnroop Drugs & Pharmaceuticals Triveni Interchem Private Limited (Group Of Triveni... Titan Pharma India Private Limited HRV Global Life Sciences Private Limited Kores (India) Limited