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ChemicalBook > Product Catalogue >API >Anesthetic Agents >Local anesthetics >Dyclonine hydrochloride

Dyclonine hydrochloride

Dyclonine hydrochloride Structure
  • ₹7000 - ₹12145.65
  • Product name: Dyclonine hydrochloride
  • CAS: 536-43-6
  • MF: C18H28ClNO2
  • MW: 325.87
  • EINECS:208-633-6
  • MDL Number:MFCD00035386
  • Synonyms:DYCLONINE HYDROCHLORIDE;LABOTEST-BB LT00771942;1-(4-BUTOXYPHENYL)-3-(1-PIPERIDINYL)-1-PROPANONE HCL;1-(4-BUTOXYPHENYL)-3-(1-PIPERIDINYL)-1-PROPANONE HYDROCHLORIDE;1-(4-butoxyphenyl)-3-(1-piperidinyl)-1-propanonhydrochloride ;dyclothane ;p-267 ;piperidine,1-(2-(4-butoxybenzoyl)ethyl),hydrochloride
3 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 500MG
  • 5G
  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberD4303
  • Product descriptionDyclonine Hydrochloride
  • Packaging5G
  • Price₹7000
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberD4303
  • Product descriptionDyclonine Hydrochloride
  • Packaging25G
  • Price₹11800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1849
  • Product descriptionDyclonine Hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging500MG
  • Price₹12145.65
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) D4303 Dyclonine Hydrochloride 5G ₹7000 2022-05-26 Buy
TCI Chemicals (India) D4303 Dyclonine Hydrochloride 25G ₹11800 2022-05-26 Buy
Sigma-Aldrich(India) PHR1849 Dyclonine Hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material 500MG ₹12145.65 2022-06-14 Buy

Properties

Melting point :175-176°C
storage temp. :Inert atmosphere,2-8°C
solubility :Soluble in DMSO (20 mg/ml); Water (25 mg/ml)
form :solid
color :White
Water Solubility :Partly soluble in water. Soluble in chloroform, ethanol, acetone and methanol.
Merck :14,3473
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 2 months.
InChI :InChI=1S/C18H27NO2.ClH/c1-2-3-15-21-17-9-7-16(8-10-17)18(20)11-14-19-12-5-4-6-13-19;/h7-10H,2-6,11-15H2,1H3;1H
InChIKey :KNZADIMHVBBPOA-UHFFFAOYSA-N
SMILES :C1(C(=O)CCN2CCCCC2)C=CC(OCCCC)=CC=1.Cl
CAS DataBase Reference :536-43-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Dyclonine hydrochloride is the hydrochloride salt of Dyclonine. Dyclonine belongs to a kind of oral anaesthetic. It is contained in the “Sucrets” as well as some kinds of Cepacol sore throat spray as an active ingredient. Dyclonine takes effect through reversibly binding to the activated sodium channels located on the neuronal membrane. This decreases the permeability of sodium across the neuronal membrane, further increasing the threshold for excitation. Overall, Dyclonine stabilizes the membrane and inhibits depolarization, resulting in the failure of a propagated action potential and further suppressing the subsequent conduction. This causes a transient and reversible anaesthetic effect in a local area of the body.

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