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ChemicalBook > Product Catalogue >Biochemical Engineering >Polypeptide >Dynorphin A (1-13)

Dynorphin A (1-13)

Dynorphin A (1-13) Structure
  • ₹16345.75
  • Product name: Dynorphin A (1-13)
  • CAS: 72957-38-1
  • MF: C75H126N24O15
  • MW: 1603.95
  • EINECS:635-974-1
  • MDL Number:MFCD00076366
  • Synonyms:TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS;TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS 5ACOH 6H2O;TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS PORCINE;YGGFLRRIRPKLK;L-TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS;DYNORPHIN A PORCINE FRAGMENT 1-13;DYNORPHIN A(HUMAN, 1-13);DYNORPHIN A (HUMAN, 1-13) (PORCINE, RAT, BOVINE)
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Brand

  • Sigma-Aldrich(India)

Package

  • 1MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberD7017
  • Product descriptionDynorphin A Porcine Fragment 1-13 ≥97% (HPLC)
  • Packaging1MG
  • Price₹16345.75
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) D7017 Dynorphin A Porcine Fragment 1-13 ≥97% (HPLC) 1MG ₹16345.75 2022-06-14 Buy

Properties

Density :1.39±0.1 g/cm3(Predicted)
RTECS :JV7436666
storage temp. :Inert atmosphere,Store in freezer, under -20°C
form :Solid
pka :3.31±0.10(Predicted)
color :White to off-white
Water Solubility :Water: ≥ 60 mg/mL (37.41 mM)
Sequence :H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-OH
InChIKey :OVVIBUHLQIYUEU-JASZZEBFNA-N

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Dynorphin A(1-13), a tridecapeptide of the endogenous opioid peptides, has modest effects in reducing mild opiate withdrawal in humans. Previous studies revealed that dynorphin also potentiates the analgesic effect of morphine in morphine-tolerant rats and mice. The therapeutic potential of dynorphin A(1-13) is limited due to extensive metabolism by human metabolic enzymes resulting in an in vivo half-life of less than one minute. Chemical modifications of dynorphin A(1-13), such as N-methylation of Tyr1 and amidation of the C-terminus have been shown to be effective in protecting against the proteolytic enzymes in human plasma[1].

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