ELOCALCITOL
|
- ₹0
- Product name: ELOCALCITOL
- CAS: 199798-84-0
- MF: C29H43FO2
- MW: 442.65
- EINECS:
- MDL Number:MFCD09954119
- Synonyms:ELOCALCITOL;BXL 628;(1R,3E,5S)-3-[(2E)-2-[(3aS,7aS)-1-[(E,2S)-6-ethyl-6-hydroxyoct-4-en-2-yl]-7a-methyl-3a,5,6,7-tetrahydro-3H-inden-4-ylidene]ethylidene]-5-fluoro-4-methylidenecyclohexan-1-ol;Ellocalciferol;Cyclohexanol, 3-[(2E)-2-[(3aS,7aS)-1-[(1S,3E)-5-ethyl-5-hydroxy-1-methyl-3-hepten-1-yl]-3,3a,5,6,7,7a-hexahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-5-fluoro-4-methylene-, (1R,3Z,5S)-;Ro 26-9228
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|
Properties
Boiling point :568.3±50.0 °C(Predicted)
Density :1.05±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Ethanol:20.0(Max Conc. mg/mL);45.18(Max Conc. mM)
form :A crystalline solid
pka :14.04±0.40(Predicted)
color :White to off-white
Density :1.05±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Ethanol:20.0(Max Conc. mg/mL);45.18(Max Conc. mM)
form :A crystalline solid
pka :14.04±0.40(Predicted)
color :White to off-white
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
BXL-628 is an analog of vitamin D3 that has diverse biological activities. It increases death of androgen-stimulated human benign prostatic hyperplasia (BPH) cells via induction of apoptosis in a dose-dependent manner. In vivo, BXL-628 completely inhibits androgen-stimulated prostate overgrowth in a rat model of BPH. It reduces expression of IL-13 and IgE/mast cell-derived protease 1 (MMCP1) and decreases edema and leukocyte infiltration in the bladder wall in a mouse model of allergen-induced interstitial cystitis. BXL-628 also reduces the number of adherent endometrial stromal cells and decreases the total weight of endometrial lesions in a mouse model of endometriosis. Formulations containing BXL-628 are under clinical investigation for the treatment of BPH.More related product prices
ParicalcitolRelated product price
- 51117-35-2
₹23057.25
