EMBELIN
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- ₹9147.13 - ₹39381.35
- Product name: EMBELIN
- CAS: 550-24-3
- MF: C17H26O4
- MW: 294.39
- EINECS:208-979-8
- MDL Number:MFCD00016369
- Synonyms:2,5-dihydroxy-3-undecyl-p-benzoquinon ;4-dione,2,5-dihydroxy-3-undecyl-5-cyclohexadiene-1 ;embelicacid ;emberine ;APOPTOSIS ACTIVATOR III;EMBELIN;2,5-DIHYDROXY-3-UNDECYL-1,4-BENZOQUINONE;2,5-DIHYDROXY-3-UNDECYL-2,5-CYCLOHEXADIENE-1,4-DIONE
5 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
- ALFA India
Package
- 10MG
- 50MG
- ManufacturerSigma-Aldrich(India)
- Product numberE1406
- Product descriptionEmbelin ≥98% (HPLC), powder
- Packaging50MG
- Price₹39381.35
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number178493
- Product descriptionApoptosis Activator III, Embelin - CAS 550-24-3 - Calbiochem The Apoptosis Activator III, Embelin, also referenced under CAS 550-24-3, controls the biological activity of Apoptosis. This small molecule/inhibitor
- Packaging10MG
- Price₹17660.01
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberE1406
- Product descriptionEmbelin ≥98% (HPLC), powder
- Packaging10MG
- Price₹9147.13
- Updated2022-06-14
- Buy
- ManufacturerALFA India
- Product numberALF-J64074-MF
- Product descriptionEmbelin
- Packaging50mg
- Price₹36711
- Updated2022-05-26
- Buy
- ManufacturerALFA India
- Product numberALF-J64074-MA
- Product descriptionEmbelin
- Packaging10mg
- Price₹9542
- Updated2022-05-26
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | E1406 | Embelin ≥98% (HPLC), powder | 50MG | ₹39381.35 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 178493 | Apoptosis Activator III, Embelin - CAS 550-24-3 - Calbiochem The Apoptosis Activator III, Embelin, also referenced under CAS 550-24-3, controls the biological activity of Apoptosis. This small molecule/inhibitor | 10MG | ₹17660.01 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | E1406 | Embelin ≥98% (HPLC), powder | 10MG | ₹9147.13 | 2022-06-14 | Buy |
ALFA India | ALF-J64074-MF | Embelin | 50mg | ₹36711 | 2022-05-26 | Buy |
ALFA India | ALF-J64074-MA | Embelin | 10mg | ₹9542 | 2022-05-26 | Buy |
Properties
Melting point :142-143°C
Boiling point :356.15°C (rough estimate)
Density :1.131
refractive index :1.4230 (estimate)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :DMSO: >10 mg/mL
form :solid
pka :2.84±0.50(Predicted)
color :Dark orange
Sensitive :Light Sensitive
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
LogP :5.024 (est)
Boiling point :356.15°C (rough estimate)
Density :1.131
refractive index :1.4230 (estimate)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :DMSO: >10 mg/mL
form :solid
pka :2.84±0.50(Predicted)
color :Dark orange
Sensitive :Light Sensitive
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
LogP :5.024 (est)
Safety Information
Symbol(GHS): |
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Signal word: | Warning | |||||||
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Description
X-Linked inhibitor of apoptosis (XIAP) is a protein which modulates several pathways, including several related to apoptosis. Embelin is a natural benzoquinone, isolated from plants of the genus Embelia, which directly binds and inhibits XIAP (IC50 = 4.1 μM). In this way, this cell-permeable inhibitor blocks growth while activating caspases and promoting apoptosis in cancer cells expressing high levels of XIAP. Presumably in an XIAP-dependent fashion, embelin (15-50 μM) also prevents NF-κB activation by inhibiting IKK. This compound also protects against XIAP- and caspase-dependent inflammation.More related product prices
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₹9147.13-39381.35