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ChemicalBook > Product Catalogue >Biochemical Engineering >Plant extracts >EMBELIN

EMBELIN

EMBELIN Structure
  • ₹9147.13 - ₹39381.35
  • Product name: EMBELIN
  • CAS: 550-24-3
  • MF: C17H26O4
  • MW: 294.39
  • EINECS:208-979-8
  • MDL Number:MFCD00016369
  • Synonyms:2,5-dihydroxy-3-undecyl-p-benzoquinon ;4-dione,2,5-dihydroxy-3-undecyl-5-cyclohexadiene-1 ;embelicacid ;emberine ;APOPTOSIS ACTIVATOR III;EMBELIN;2,5-DIHYDROXY-3-UNDECYL-1,4-BENZOQUINONE;2,5-DIHYDROXY-3-UNDECYL-2,5-CYCLOHEXADIENE-1,4-DIONE
5 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)
  • ALFA India

Package

  • 10MG
  • 50MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberE1406
  • Product descriptionEmbelin ≥98% (HPLC), powder
  • Packaging50MG
  • Price₹39381.35
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number178493
  • Product descriptionApoptosis Activator III, Embelin - CAS 550-24-3 - Calbiochem The Apoptosis Activator III, Embelin, also referenced under CAS 550-24-3, controls the biological activity of Apoptosis. This small molecule/inhibitor
  • Packaging10MG
  • Price₹17660.01
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberE1406
  • Product descriptionEmbelin ≥98% (HPLC), powder
  • Packaging10MG
  • Price₹9147.13
  • Updated2022-06-14
  • Buy
  • ManufacturerALFA India
  • Product numberALF-J64074-MF
  • Product descriptionEmbelin
  • Packaging50mg
  • Price₹36711
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-J64074-MA
  • Product descriptionEmbelin
  • Packaging10mg
  • Price₹9542
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) E1406 Embelin ≥98% (HPLC), powder 50MG ₹39381.35 2022-06-14 Buy
Sigma-Aldrich(India) 178493 Apoptosis Activator III, Embelin - CAS 550-24-3 - Calbiochem The Apoptosis Activator III, Embelin, also referenced under CAS 550-24-3, controls the biological activity of Apoptosis. This small molecule/inhibitor 10MG ₹17660.01 2022-06-14 Buy
Sigma-Aldrich(India) E1406 Embelin ≥98% (HPLC), powder 10MG ₹9147.13 2022-06-14 Buy
ALFA India ALF-J64074-MF Embelin 50mg ₹36711 2022-05-26 Buy
ALFA India ALF-J64074-MA Embelin 10mg ₹9542 2022-05-26 Buy

Properties

Melting point :142-143°C
Boiling point :356.15°C (rough estimate)
Density :1.131
refractive index :1.4230 (estimate)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :DMSO: >10 mg/mL
form :solid
pka :2.84±0.50(Predicted)
color :Dark orange
Sensitive :Light Sensitive
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
LogP :5.024 (est)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:
P201 Obtain special instructions before use.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

X-Linked inhibitor of apoptosis (XIAP) is a protein which modulates several pathways, including several related to apoptosis. Embelin is a natural benzoquinone, isolated from plants of the genus Embelia, which directly binds and inhibits XIAP (IC50 = 4.1 μM). In this way, this cell-permeable inhibitor blocks growth while activating caspases and promoting apoptosis in cancer cells expressing high levels of XIAP. Presumably in an XIAP-dependent fashion, embelin (15-50 μM) also prevents NF-κB activation by inhibiting IKK. This compound also protects against XIAP- and caspase-dependent inflammation.

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