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ChemicalBook > Product Catalogue >API >Digestive system drugs >Antacid and Mucosal protective Drugs >Esomeprazole sodium

Esomeprazole sodium

Esomeprazole sodium Structure
  • ₹0
  • Product name: Esomeprazole sodium
  • CAS: 161796-78-7
  • MF: C34H36MgN6O6S2
  • MW: 713.12
  • EINECS:620-470-6
  • MDL Number:MFCD19705377
  • Synonyms:(S)-OMeprazole sodiuM;1H-BENZIMIDAZOLE, 5-METHOXY-2-[[(4-METHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYL]SULFINYL]-, SODIUM SALT;ESOMEPRAZOLE SODIUM;Esomeprazoleandsalts;5-Methoxy-2-((S)-((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl-1H-benzimidazole sodium salt;SodiuM (S)-6-Methoxy-2-(((4-Methoxy-3,5-diMethylpyridin-2-yl)Methyl)sulfinyl)benzo[d]iMidazol-1-ide;odiuM (R)-6-Methoxy-2-(((4-Methoxy-3,5-diMethylpyridin-2-yl)Methyl)sulfinyl)benzo[d]iMidazol-1-ide;EsoMeprazole sod
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :156 °C (approx)
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :DMSO (Slightly, Sonicated), Methanol (Slightly), Water (Slightly)
form :Solid
color :Pale Beige to Brown
Stability :Hygroscopic
InChI :InChI=1S/C17H18N3O3S.Na/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;/h5-8H,9H2,1-4H3;/q-1;+1
InChIKey :RYXPMWYHEBGTRV-UHFFFAOYSA-N
SMILES :C1(S(=O)CC2=NC=C(C)C(OC)=C2C)N([Na])C2=C(C=C(C=C2)OC)N=1

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger GHS hazard pictograms P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H412 Harmful to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 3 P273, P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P363 Wash contaminated clothing before reuse.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Esomeprazole sodium is a commonly used anti-ulcer drug. It was successfully developed by AstraZeneca for the first time. It is a proton pump inhibitor. The drug of choice for related diseases.
(S)-Omeprazole is the (S)-enantiomer of Omeprazole (O635000) a gastric proton-pump inhibitor. (S)-Omeprazole is more potent that its (R)-enantiomer and is used in the treatment of gastroesophageal ref lux disease as well as gastrointestinal ulcers associated with Crohn's disease.

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Suppliers and manufacturers

Jigs Chemical ltd Micro Orgo Chem Aurobindo Pharma Limited Glenmark Pharmaceuticals Limited Vivimed Labs Ltd Lee Pharma Ltd Macleods Pharmaceuticals Limited Hetero Drugs Limited Prachi Pharmaceuticals Pvt Ltd Integrin Life Sciences. Pvt. Ltd.