Fluvastatin
- ₹0
- Product name: Fluvastatin
- CAS: 93957-54-1
- MF: C24H26FNO4
- MW: 411.47
- EINECS:695-664-7
- MDL Number:MFCD00869941
- Synonyms:FLUVASTATIN;FLUVASTATIN NA;FLUVASTATIN SODIUM;METHYL-(+/-)-(E)-7-[3'-(4-FLUOROPHENYL)-1'-(1-METHYLETHYL)INDOL-2'-YL]-3,5-DIHYDROXY-6-HEPTENOATE;FLUVASTATIN[METHYL-(±)-(E)-7-[3’-(4”-FLUOROPHENYL )-1’-(1”-METHYLETHYL)INDOL-2’-YL]-3,5- DIHYDROXY-6- HEPTENOATE ];FluvastatinC24H26FN04;(3S,5R,E)-7-(3-(4-fluorophenyl)-1-isopropyl-1H-indol-2-yl)-3,5-dihydroxyhept-6-enoic acid;Lipaxan
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Properties
Melting point :193.9-196.9 °C
Boiling point :681.8±55.0 °C(Predicted)
Density :1.23±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Water 25 mg/ml DMSO 100 mg/ml Ethanol 25 mg/ml
form :Powder
pka :4.27±0.10(Predicted)
color :Light yellow to yellow
CAS DataBase Reference :93957-54-1(CAS DataBase Reference)
EPA Substance Registry System :6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]- 3,5-dihydroxy-, (3R,5S,6E)-rel- (93957-54-1)
Boiling point :681.8±55.0 °C(Predicted)
Density :1.23±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Water 25 mg/ml DMSO 100 mg/ml Ethanol 25 mg/ml
form :Powder
pka :4.27±0.10(Predicted)
color :Light yellow to yellow
CAS DataBase Reference :93957-54-1(CAS DataBase Reference)
EPA Substance Registry System :6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]- 3,5-dihydroxy-, (3R,5S,6E)-rel- (93957-54-1)
Safety Information
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Description
Fluvastatin is an HMGCR (HMG-CoA reductase) inhibitor. The compound is described to inhibit cell proliferation, illicit apoptosis, and protect against oxidative stress. Human hepatocellular carcinoma cell (HCC) studies indicate that Fluvastatin induces G2/M phase arrest. In the presence of Fluvastatin, HCC cells show a decrease of Bcl-2 and procaspase-9 expression, and an increase in Bax, cleaved caspase-3, and cytochrome c.More related product prices
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