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ChemicalBook > Product Catalogue >API >Antipyretic analgesics >Nonsteroidal Anti-Inflammatory Drugs (NSAIDS) >Indometacin

Indometacin

Indometacin Structure
  • ₹3399.05 - ₹64084
  • Product name: Indometacin
  • CAS: 53-86-1
  • MF: C19H16ClNO4
  • MW: 357.79
  • EINECS:200-186-5
  • MDL Number:MFCD00057095
  • Synonyms:indomethacin crystalline;indomethacin methanol solution;indomethacin usp;AURORA KA-6542;INDOMETACIN;LABOTEST-BB LT00244830;INDOMETHACIN BP99;N-(4-Chlorobenzoyl)-4-Methoxyphenyl-Hydrazine
12 prices
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 500MG
  • 5G
  • 10G
  • 25G
  • 100G
  • 500G
  • ManufacturerTCI Chemicals (India)
  • Product numberI0655
  • Product descriptionIndomethacin
  • Packaging25G
  • Price₹4000
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberI0655
  • Product descriptionIndomethacin
  • Packaging100G
  • Price₹11800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberI0655
  • Product descriptionIndomethacin
  • Packaging500G
  • Price₹15600
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberI7378
  • Product descriptionIndomethacin 98.5-100.5% (in accordance with EP)
  • Packaging100G
  • Price₹64084
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberI8280
  • Product descriptionIndomethacin meets USP testing specifications
  • Packaging100G
  • Price₹42444.83
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberI7378
  • Product descriptionIndomethacin 98.5-100.5% (in accordance with EP)
  • Packaging25G
  • Price₹24691.83
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number405268
  • Product descriptionIndomethacin - CAS 53-86-1 - Calbiochem A non-steroidal anti-inflammatory, cell permeable, antipyretic agent.
  • Packaging10G
  • Price₹14899.99
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberI8280
  • Product descriptionIndomethacin meets USP testing specifications
  • Packaging25G
  • Price₹13596.2
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberI7378
  • Product descriptionIndomethacin 98.5-100.5% (in accordance with EP)
  • Packaging10G
  • Price₹13542.08
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1247
  • Product descriptionIndomethacin Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging500MG
  • Price₹10695.1
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberI7378
  • Product descriptionIndomethacin 98.5-100.5% (in accordance with EP)
  • Packaging5G
  • Price₹8151.23
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberI8280
  • Product descriptionIndomethacin meets USP testing specifications
  • Packaging5G
  • Price₹3399.05
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) I0655 Indomethacin 25G ₹4000 2022-05-26 Buy
TCI Chemicals (India) I0655 Indomethacin 100G ₹11800 2022-05-26 Buy
TCI Chemicals (India) I0655 Indomethacin 500G ₹15600 2022-05-26 Buy
Sigma-Aldrich(India) I7378 Indomethacin 98.5-100.5% (in accordance with EP) 100G ₹64084 2022-06-14 Buy
Sigma-Aldrich(India) I8280 Indomethacin meets USP testing specifications 100G ₹42444.83 2022-06-14 Buy
Sigma-Aldrich(India) I7378 Indomethacin 98.5-100.5% (in accordance with EP) 25G ₹24691.83 2022-06-14 Buy
Sigma-Aldrich(India) 405268 Indomethacin - CAS 53-86-1 - Calbiochem A non-steroidal anti-inflammatory, cell permeable, antipyretic agent. 10G ₹14899.99 2022-06-14 Buy
Sigma-Aldrich(India) I8280 Indomethacin meets USP testing specifications 25G ₹13596.2 2022-06-14 Buy
Sigma-Aldrich(India) I7378 Indomethacin 98.5-100.5% (in accordance with EP) 10G ₹13542.08 2022-06-14 Buy
Sigma-Aldrich(India) PHR1247 Indomethacin Pharmaceutical Secondary Standard; Certified Reference Material 500MG ₹10695.1 2022-06-14 Buy
Sigma-Aldrich(India) I7378 Indomethacin 98.5-100.5% (in accordance with EP) 5G ₹8151.23 2022-06-14 Buy
Sigma-Aldrich(India) I8280 Indomethacin meets USP testing specifications 5G ₹3399.05 2022-06-14 Buy

Properties

Melting point :158-162 °C
Boiling point :499.4±45.0 °C(Predicted)
Density :1.2135 (rough estimate)
refractive index :1.6800 (estimate)
storage temp. :Store at RT
solubility :ethanol: 50 mg/mL, clear, yellow-green
form :White to off-white powder
pka :4.5(at 25℃)
color :White to Light yellow to Light orange
Water Solubility :Soluble in acetone (40 mg/mL - clear, yellow solution), ethanol (20 mg/mL), ether, castor oil; Soluble in chloroform (50 mg/mL - clear, yellow, extremely viscous solution); decomposed by strong alkali but stable in neutral or slightly acidic media; insoluble in water.
Sensitive :Light Sensitive
Merck :14,4968
BRN :497341
BCS Class :2
Stability :Stable. Incompatible with strong oxidizing agents.
InChIKey :CGIGDMFJXJATDK-UHFFFAOYSA-N
CAS DataBase Reference :53-86-1(CAS DataBase Reference)
NIST Chemistry Reference :Indomethacin(53-86-1)
EPA Substance Registry System :Indomethacin (53-86-1)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

Indomethacin is a non-selective COX inhibitor. The IC50 values for ovine COX-1 and -2 are 0.1 and 6 μM, respectively. The IC50 values for human recombinant COX-1 and -2 are 1.67 and 24.6 μM, respectively.

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